Anadol 50 mg (Capsule)
Unit Price: ৳ 8.07 (4 x 10: ৳ 322.80)
Strip Price: ৳ 80.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Tramadol hydrochloride |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Treatment of moderate to severe painful conditions
- Postoperative pain
- Colic and spastic pain
- Cancer pain
- Joint pain
- Neck and back pain
- Pain associated with osteoporosis
Pharmacology
- Centrally acting synthetic analgesic compound
- Inhibition of reuptake of neurotransmitters- serotonin and noradrenaline
- Modification of transmission of pain impulses
- Activation of descending serotonergic pathways and noradrenergic pathways
- Stimulation of mu-opioid receptors
- Modulation of central monoaminergic inhibitory pathways
Dosage & Administration
- Usual doses of 50 to 100 mg every four to six hours
- Initial dose of 100 mg for acute pain
- Initial dose of 50 mg for chronic painful conditions
- Maximum total daily dosage by mouth of 400 mg
- Sustained Release Capsule or Tablet dosage of one every 12 hours
- Injection dose of 50-100 mg every 4 to 6 hours
- Suppository dosage of 100 mg Tramadol Hydrochloride 6 hourly for adults
Interaction
- Contraindication with monoamine oxidase (MAO) inhibitors
- Potential interaction with carbamazepine
Contraindications
- Hypersensitivity to Tramadol
- Contraindicated in acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs
Side Effects
- Dizziness/vertigo
- Nausea
- Constipation
- Headache
- Somnolence
- Vomiting
- Pruritus
- CNS stimulation
- Asthenia
- Sweating
- Dyspepsia
- Dry mouth
- Diarrhea
- Malaise
- Allergic reaction
- Weight loss
- Vasodilatation
- Palpitations
- Abdominal pain
- Anorexia
- Flatulence
- GI bleeding
- Hepatitis
- Stomatitis
Pregnancy & Lactation
- Tramadol crosses the placenta
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies the risk to the fetus
- Not recommended during breastfeeding
Precautions & Warnings
- Cautious administration in patients at risk for respiratory depression
- Not recommended for patients dependent on opioids
- Use with caution when administering to patients receiving CNS depressants
- Use with great caution in patients taking MAO inhibitors
- Use with caution in patients with increased intracranial pressure or head injury, and patients with acute abdominal conditions
Use in Special Populations
- Use in children from the age of 1 year at a dose of 1-2 mg/kg body weight
- Suppository (100 mg Tramadol) should not be administered in children and adolescents below the age of 14 years
- Anadol 100 mg SR Capsules have not been studied in children
- Safety and efficacy not established in children
Therapeutic Class
- Opioid analgesics
Storage Conditions
- Keep below 30°C temperature
- Keep away from light and moisture
- Keep out of the reach of children