Anadol 100 mg (Suppository)

Unit Price: ৳ 15.10 (4 x 5: ৳ 302.00)

Medicine Details

Category Details
Generic Tramadol hydrochloride
Company Square pharmaceuticals plc
Also available as
Anadol 50 mg capsule Anadol sr 100 mg capsule Anadol 100 mg injection

Indications

  • Moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

  • Centrally acting synthetic analgesic compound
  • Inhibition of serotonin and noradrenaline reuptake
  • Activation of descending serotonergic pathways
  • Indirect modulation of central monoaminergic inhibitory pathways
  • Stimulation of mu-opioid receptors

Dosage & Administration

  • Usual doses of 50-100 mg every 4-6 hours
  • Initial dose of 100 mg for acute pain
  • Initial dose of 50 mg for chronic painful conditions
  • Sustained release capsule or tablet every 12 hours
  • Injection dose of 50-100 mg every 4-6 hours
  • Suppository dose of 100 mg every 6 hours for adults

Interaction

  • Contraindicated with monoamine oxidase (MAO) inhibitors
  • Increased metabolism when concomitantly administered with carbamazepine

Contraindications

  • Hypersensitivity to Tramadol
  • Acute intoxication with alcohol or certain drugs

Side Effects

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Somnolence
  • Vomiting
  • Pruritus
  • CNS stimulation
  • Asthenia
  • Sweating
  • Dyspepsia
  • Dry mouth
  • Diarrhea
  • Malaise
  • Allergic reaction
  • Weight loss
  • Vasodilatation
  • Palpitations
  • Abdominal pain
  • Anorexia
  • Flatulence
  • GI bleeding
  • Hepatitis
  • Stomatitis

Pregnancy & Lactation

  • Crosses placenta
  • No adequate and well-controlled studies in pregnant women
  • Potential benefit justifies risk to the fetus
  • Should not be administered during breastfeeding

Precautions & Warnings

  • Respiratory depression risk
  • Not recommended for opioid-dependent patients
  • Caution with CNS depressants
  • Caution with MAO inhibitors
  • Caution with increased intracranial pressure or head injury
  • Caution with acute abdominal conditions

Use in Special Populations

  • Dose of 1-2 mg/kg body weight in children from age 1 year
  • Suppository contraindicated in children and adolescents below age 14 years
  • Anadol 100 mg SR Capsules not studied in children

Therapeutic Class

  • Opioid analgesics

Storage Conditions

  • Keep below 30°C
  • Away from light & moisture
  • Keep out of the reach of children

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