Lucidol 50 mg (Capsule)
Medicine Details
Category | Details |
---|---|
Generic | Tramadol hydrochloride |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- Postoperative pain
- Colic and spastic pain
- Cancer pain
- Joint pain
- Neck and back pain
- Pain associated with osteoporosis
Pharmacology
Centrally acting synthetic analgesic compound. It inhibits the re uptake of neurotransmitters- serotonin and noradrenaline. It modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in analgesia.
Dosage & Administration
- Usual doses are 50 to 100 mg every four to six hours
- Total daily dosage by mouth should not exceed 400 mg
- One SR capsule or tablet every 12 hours
- Injection dose of 50-100 mg may be given every 4 to 6 hours
- Adults usual dose for suppository is 100 mg Tramadol Hydrochloride 6 hourly
Interaction
Monoamine oxidase (MAO) inhibitors represent the only drug class not recommended for combination with Lucidol. Concomitant administration of carbamazepine with Lucidol causes a significant increase in Lucidol metabolism.
Contraindications
- Hypersensitivity to this drug
- Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs
Side Effects
- Dizziness/vertigo
- Nausea
- Constipation
- Headache
- Somnolence
- Vomiting
- Pruritus
- CNS stimulation
- Asthenia
- Sweating
- Dyspepsia
- Dry mouth
- Diarrhoea
- Malaise
- Allergic reaction
- Weight loss
- Vasodilatation
- Palpitations
- Abdominal pain
- Anorexia
- Flatulence
- GI bleeding
- Hepatitis
- Stomatitis
Pregnancy & Lactation
Safe use of Tramadol in pregnancy has not been established. Tramadol should not be administered during breast feeding as Tramadol and its metabolites have been detected in breast milk.
Precautions & Warnings
- Respiratory depression
- Opioid dependence
- Concomitant CNS depressants
- Concomitant MAO inhibitors
- Caution in patients with increased intracranial pressure or head injury and patients with acute abdominal conditions
Use in Special Populations
- Lucidol can be given in a dose of 1-2 mg/kg body weight in children from the age of 1 year
- Suppository (100 mg Lucidol) should not be administered in children and adolescents below the age of 14 years
Therapeutic Class
Opioid analgesics
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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