Pendol 50 mg (Capsule)
Unit Price: ৳ 6.02 (3 x 10: ৳ 180.60)
Strip Price: ৳ 60.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Tramadol hydrochloride |
| Company | Alco pharma ltd |
Title and Categories
- Pendol
- Pain Relief
- Opioid Analgesic
Dosage Form
- Capsule
- Tablet
- Sustained Release Capsule
- Injection
- Suppository
Indications
- Postoperative pain
- Colic and spastic pain
- Cancer pain
- Joint pain
- Neck and back pain
- Pain associated with osteoporosis
Pharmacology
- Centrally acting synthetic analgesic
- Inhibits reuptake of serotonin and noradrenaline
- Modifies pain impulse transmission
- Activates descending serotonergic pathways
- Mediates via stimulation of mu-opioid receptors
Interaction
- MAO inhibitors not recommended for combination
- Potentiation with carbamazepine
Contraindications
- Hypersensitivity to Tramadol
- Acute intoxication with certain drugs
Side Effects
- Dizziness/vertigo
- Nausea
- Constipation
- Headache
- Somnolence
- Vomiting
- Pruritus
- CNS stimulation
- Asthenia
- Sweating
- Dyspepsia
- Dry mouth
- Diarrhoea
- Malaise
- Allergic reaction
- Weight loss
- Vasodilatation
- Palpitations
- Abdominal pain
- Anorexia
- Flatulence
- GI bleeding
- Hepatitis
- Stomatitis
Usability Features
- Safe use not established in pregnancy
- Tramadol crosses placenta
- Avoid use during breastfeeding
- Cautious administration in patients at risk for respiratory depression
- Not recommended for patients dependent on opioids
- Cautious use with CNS depressants
- Cautious use with MAO inhibitors
- Cautious use in patients with increased intracranial pressure or head injury
- Cautious use in patients with acute abdominal conditions
- Dosage varies based on pain severity
Pregnancy & Lactation
- Safe use not established in pregnancy
- Crosses placenta
- Not recommended during breastfeeding
Special Populations
- Can be given to children from the age of 1 year
- Suppository not for children below 14 years
- SR Capsules not studied in children
Technical Specifications
- Maximum daily dosage by mouth should not exceed 400 mg
- Injection dose 50-100 mg every 4 to 6 hours
- Suppository dose is 100 mg Tramadol Hydrochloride every 6 hours
- Storage temperature below 30°C
Warnings
- Cautious administration in patients at risk for respiratory depression
- Not recommended for patients dependent on opioids
- Cautious use with CNS depressants
- Cautious use with MAO inhibitors
- Cautious use in patients with increased intracranial pressure or head injury
- Cautious use in patients with acute abdominal conditions