Syndol 50 mg (Capsule)

Unit Price: ৳ 8.50 (3 x 10: ৳ 255.00)
Strip Price: ৳ 85.00

Medicine Details

Category Details
Generic Tramadol hydrochloride
Company Healthcare pharmaceuticals ltd
Also available as
Syndol 100 mg injection

Indications

  • Treatment of moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

  • Centrally acting synthetic analgesic compound
  • Inhibition of reuptake of neurotransmitters
  • Stimulation of mu-opioid receptors
  • Modulation of central monoaminergic inhibitory pathways

Dosage & Administration

  • Usual doses of 50 to 100 mg every four to six hours
  • Initial dose of 100 mg for acute pain
  • Initial dose of 50 mg for chronic painful conditions
  • Sustained release capsule or tablet available
  • Injection dosage of 50-100 mg every 4 to 6 hours
  • Suppository administration for adults and children

Interaction

  • Monoamine oxidase (MAO) inhibitors not recommended for combination
  • Concomitant administration of carbamazepine

Contraindications

  • Hypersensitivity to Tramadol
  • Acute intoxication with certain drugs

Side Effects

  • Common: dizziness, nausea, constipation, headache
  • Less common: malaise, allergic reaction, weight loss

Pregnancy & Lactation

  • Safety in pregnancy not established
  • Crosses the placenta
  • Not recommended during breastfeeding

Precautions & Warnings

  • Risk of respiratory depression
  • Not recommended for opioid dependent patients
  • Use with caution with CNS depressants
  • Use with caution in patients taking MAO inhibitors

Use in Special Populations

  • Safe use in children from the age of 1 year
  • Suppository not recommended in children and adolescents below the age of 14 years
  • Safety and efficacy not established in children for 100 mg SR Capsules

Therapeutic Class

  • Opioid analgesics

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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