Tamadol 50 mg (Capsule)
Unit Price: ৳ 7.25 (30's pack: ৳ 217.50)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tramadol hydrochloride |
| Company | Mystic pharmaceuticals ltd |
Indications
- Treatment of moderate to severe painful conditions
- Postoperative pain
- Colic and spastic pain
- Cancer pain
- Joint pain
- Neck and back pain
- Pain associated with osteoporosis
Pharmacology
- Centrally acting synthetic analgesic compound
- Inhibition of reuptake of neurotransmitters - serotonin and noradrenaline
- Modification of pain impulse transmission
- Activation of descending serotonergic and noradrenergic pathways
- Stimulation of mu-opioid receptors
- Modulation of central monoaminergic inhibitory pathways
Dosage & Administration
- Usual doses of 50 to 100 mg every four to six hours
- Initial dose of 100 mg for acute pain
- Initial dose of 50 mg for chronic painful conditions
- Total daily dosage by mouth should not exceed 400 mg
- Sustained release capsule or tablet to be taken every 12 hours
- Injection dose of 50-100 mg every 4 to 6 hours
- Usual dose of 100 mg Tramadol Hydrochloride for adults via suppository every 6 hours
- Higher daily doses for cancer pain and severe postoperative pain
Interaction
- Monoamine oxidase (MAO) inhibitors as contraindicated drug class
- Concomitant administration of carbamazepine affects Tramadol metabolism
Contraindications
- Hypersensitivity to the drug
- Acute intoxication with alcohol, hypnotics, opioids, or psychotropic drugs
Side Effects
- Dizziness/vertigo
- Nausea
- Constipation
- Headache
- Somnolence
- Vomiting
- Pruritus
- CNS stimulation
- Asthenia
- Sweating
- Dyspepsia
- Dry mouth
- Diarrhoea
- Malaise
- Allergic reaction
- Weight loss
- Vasodilatation
- Palpitations
- Abdominal pain
- Anorexia
- Flatulence
- GI bleeding
- Hepatitis
- Stomatitis
Pregnancy & Lactation
- Crosses the placenta
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies risk to the fetus
- Not recommended during breastfeeding
Precautions & Warnings
- Respiratory depression risk
- Not recommended for opioid-dependent patients
- Caution with concomitant CNS depressants
- Great caution with concomitant use of MAO inhibitors
- Caution in patients with increased intracranial pressure, head injury, or acute abdominal conditions
Use in Special Populations
- Can be given in children from the age of 1 year
- Suppository not to be administered in children and adolescents below the age of 14 years
- 100 mg SR Capsules not studied in children, therefore not recommended
Therapeutic Class
- Opioid analgesics
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children