Tamadol 50 mg (Capsule)

Unit Price: ৳ 7.25 (30's pack: ৳ 217.50)

Medicine Details

Category Details
Generic Tramadol hydrochloride
Company Mystic pharmaceuticals ltd

Indications

  • Treatment of moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

  • Centrally acting synthetic analgesic compound
  • Inhibition of reuptake of neurotransmitters - serotonin and noradrenaline
  • Modification of pain impulse transmission
  • Activation of descending serotonergic and noradrenergic pathways
  • Stimulation of mu-opioid receptors
  • Modulation of central monoaminergic inhibitory pathways

Dosage & Administration

  • Usual doses of 50 to 100 mg every four to six hours
  • Initial dose of 100 mg for acute pain
  • Initial dose of 50 mg for chronic painful conditions
  • Total daily dosage by mouth should not exceed 400 mg
  • Sustained release capsule or tablet to be taken every 12 hours
  • Injection dose of 50-100 mg every 4 to 6 hours
  • Usual dose of 100 mg Tramadol Hydrochloride for adults via suppository every 6 hours
  • Higher daily doses for cancer pain and severe postoperative pain

Interaction

  • Monoamine oxidase (MAO) inhibitors as contraindicated drug class
  • Concomitant administration of carbamazepine affects Tramadol metabolism

Contraindications

  • Hypersensitivity to the drug
  • Acute intoxication with alcohol, hypnotics, opioids, or psychotropic drugs

Side Effects

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Somnolence
  • Vomiting
  • Pruritus
  • CNS stimulation
  • Asthenia
  • Sweating
  • Dyspepsia
  • Dry mouth
  • Diarrhoea
  • Malaise
  • Allergic reaction
  • Weight loss
  • Vasodilatation
  • Palpitations
  • Abdominal pain
  • Anorexia
  • Flatulence
  • GI bleeding
  • Hepatitis
  • Stomatitis

Pregnancy & Lactation

  • Crosses the placenta
  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy only if potential benefit justifies risk to the fetus
  • Not recommended during breastfeeding

Precautions & Warnings

  • Respiratory depression risk
  • Not recommended for opioid-dependent patients
  • Caution with concomitant CNS depressants
  • Great caution with concomitant use of MAO inhibitors
  • Caution in patients with increased intracranial pressure, head injury, or acute abdominal conditions

Use in Special Populations

  • Can be given in children from the age of 1 year
  • Suppository not to be administered in children and adolescents below the age of 14 years
  • 100 mg SR Capsules not studied in children, therefore not recommended

Therapeutic Class

  • Opioid analgesics

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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