Tranal 100 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 20.08 (1 x 5: ৳ 100.40)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tramadol hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Moderate to severe painful conditions
- Postoperative pain
- Colic and spastic pain
- Cancer pain
- Joint pain
- Neck and back pain
- Pain associated with osteoporosis
Pharmacology
- Centrally acting synthetic analgesic compound
- Inhibit re-uptake of neurotransmitters
- Modifies transmission of pain impulses
- Stimulation of mu-opioid receptors
- Modulation of central monoaminergic inhibitory pathways
Dosage & Administration
- Usual doses of 50 to 100 mg every 4-6 hours
- Initial dose of 100 mg for acute pain
- Initial dose of 50 mg for chronic painful conditions
- Total daily dosage by mouth should not exceed 400 mg
- Sustained release capsule or tablet for 12-hour relief
- Injection dosage of 50-100 mg every 4-6 hours
- Maximum total daily dose of 600 mg for postoperative pain
- Rectal suppository administration: usual dose of 100 mg every 6 hours
Interaction
Contraindications with monoamine oxidase (MAO) inhibitors
Contraindications
- Hypersensitivity to the drug
- Acute intoxication with alcohol, hypnotics, opioids, or psychotropic drugs
Side Effects
- Dizziness/vertigo
- Nausea
- Constipation
- Headache
- Somnolence
- Vomiting
- Pruritus
- CNS stimulation
- Asthenia
- Sweating
- Dyspepsia
- Dry mouth
- Diarrhoea
- Malaise
- Allergic reaction
- Weight loss
- Vasodilatation
- Palpitations
- Abdominal pain
- Anorexia
- Flatulence
- GI bleeding
- Hepatitis
- Stomatitis
Pregnancy & Lactation
- Not established safe use in pregnancy
- Crosses the placenta
- No adequate and well-controlled studies in pregnant women
- Risk to the foetus should justify potential benefit
- Not recommended during breastfeeding
Precautions & Warnings
- Cautious administration in patients at risk for respiratory depression
- Not recommended for opioid-dependent patients
- Caution with concomitant CNS depressants
- Great caution with concomitant MAO inhibitors
- Caution in patients with increased intracranial pressure or head injury
- Caution in patients with acute abdominal conditions
Use in Special Populations
- Can be given in children from the age of 1 year
- Suppository should not be given to children and adolescents below 14 years
- Tranal 100 mg SR Capsules not studied in children
Therapeutic Class
Opioid analgesics
Storage Conditions
Keep below 30°C temperature, away from light & moisture, and out of the reach of children