Trumen 50 mg (Capsule)

Unit Price: ৳ 7.56 (3 x 10: ৳ 226.80)
Strip Price: ৳ 75.60

Medicine Details

Indications

  • Moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

Centrally acting synthetic analgesic compound

Mode of Action

  • Inhibits reuptake of neurotransmitters - serotonin and noradrenaline
  • Modifies transmission of pain impulses
  • Stimulates mu-opioid receptors
  • Modulates central monoaminergic inhibitory pathways

Dosage & Administration

  • Usual doses of 50 to 100 mg every 4 to 6 hours
  • Initial dose of 100 mg for acute pain, 50 mg for chronic pain
  • Sustained Release Capsule: One SR capsule every 12 hours
  • Injection dose of 50-100 mg every 4 to 6 hours
  • Suppository for adults: usual dose of 100 mg every 6 hours

Interaction

Contraindicated with monoamine oxidase (MAO) inhibitors

Contraindications

  • Hypersensitivity to the drug
  • Acute intoxication with alcohol, hypnotics, opioids, or psychotropic drugs

Side Effects

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Somnolence
  • Vomiting
  • Pruritus
  • CNS stimulation
  • Asthenia
  • Sweating
  • Dyspepsia
  • Dry mouth
  • Diarrhea
  • Malaise
  • Allergic reaction
  • Weight loss
  • Vasodilatation
  • Palpitations
  • Abdominal pain
  • Anorexia
  • Flatulence
  • GI bleeding
  • Hepatitis
  • Stomatitis

Pregnancy & Lactation

  • Unsafe in pregnancy
  • Crosses the placenta
  • Risk to the fetus
  • Detected in breast milk

Precautions & Warnings

  • Respiratory depression risk
  • Not recommended for opioid-dependent patients
  • Use caution with CNS depressants
  • Use caution with MAO inhibitors
  • Caution in patients with increased intracranial pressure, head injury, or acute abdominal conditions

Use in Special Populations

  • Can be given in children from the age of 1 year

Therapeutic Class

Opioid analgesics

Storage Conditions

Keep below 30°C temperature, away from light & moisture

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