Trumen 100 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 22.14 (1 x 5: ৳ 110.72)

Medicine Details

Category Details
Generic Tramadol hydrochloride
Company General pharmaceuticals ltd
Also available as
Trumen 50 mg capsule

Indications

  • Treatment of moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

  • Centrally acting synthetic analgesic compound
  • Inhibits reuptake of neurotransmitters
  • Modifies transmission of pain impulses
  • Stimulates mu-opioid receptors
  • Modulates central monoaminergic inhibitory pathways

Dosage & Administration

  • Usual doses of 50 to 100 mg every four to six hours
  • Initial dose of 100 mg for acute pain
  • Initial dose of 50 mg for chronic painful conditions
  • Total daily dosage by mouth should not exceed 400 mg
  • Sustained release capsule or tablet to be taken every 12 hours
  • Injection dose of 50-100 mg every 4 to 6 hours
  • Suppository administered rectally with usual adult dose of 100 mg Tramadol Hydrochloride 6 hourly

Interaction

  • Monoamine oxidase (MAO) inhibitors not recommended for combination
  • Concomitant administration of carbamazepine increases Trumen metabolism

Contraindications

  • Hypersensitivity to the drug
  • Acute intoxication with certain substances

Side Effects

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Somnolence
  • Vomiting
  • Pruritus
  • CNS stimulation
  • Asthenia
  • Sweating
  • Dyspepsia
  • Dry mouth
  • Diarrhoea
  • Less commonly occurring side-effects include malaise, allergic reaction, weight loss, vasodilatation, palpitations, abdominal pain, anorexia, flatulence, GI bleeding, hepatitis, stomatitis

Pregnancy & Lactation

  • Safe use in pregnancy not established
  • Crosses the placenta
  • No adequate and well-controlled studies in pregnant women
  • Should be used during pregnancy only if the potential benefit justifies the risk to the fetus
  • Should not be administered during breastfeeding

Precautions & Warnings

  • Respiratory depression risk
  • Not recommended for patients dependent on opioids
  • Use with caution and in reduced dosages when administering to patients receiving CNS depressants
  • Use with great caution in patients taking MAO inhibitors
  • Use with caution in patients with increased intracranial pressure or head injury and patients with acute abdominal conditions

Use in Special Populations

  • Can be given in children from the age of 1 year
  • Suppository (100 mg Trumen) should not be administered in children and adolescents below the age of 14 years
  • Trumen 100 mg SR Capsules have not been studied in children

Therapeutic Class

  • Opioid analgesics

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

Related Brands