Betanol 25 mg (Tablet)

Unit Price: ৳ 0.45 (20 x 10: ৳ 90.00)
Strip Price: ৳ 4.50

Medicine Details

Indications

  • Management of hypertension
  • Long-term management of angina pectoris
  • Managing hemodynamically stable patients with acute myocardial infarction

Pharmacology

  • Beta1 selective (cardioselective) beta-adrenergic receptor antagonist
  • Poor penetration of cell membranes due to high hydrophilicity

Dosage & Administration

  • Initial dose: 50 mg once daily for hypertension
  • Initial dose: 50 mg once daily for angina pectoris
  • Initial dose: 5 mg intravenous injection for acute myocardial infarction

Interactions

  • Additive effect with catecholamine-depleting drugs
  • Additive effect with calcium channel blockers
  • Risk of severe bradycardia when combined with disopyramide
  • Potential additive effects with amiodarone
  • Potential exacerbation of rebound hypertension with clonidine withdrawal
  • Decreased hypotensive effects with prostaglandin synthase inhibiting drugs
  • Increased risk of severe allergic reaction in patients with history of anaphylaxis

Contraindications

  • Sinus bradycardia
  • Heart block greater than first degree
  • Cardiogenic shock
  • Overt cardiac failure
  • Hypersensitivity to atenolol or its components

Side Effects

  • Agranulocytosis
  • Allergic reactions like fever, sore throat, respiratory distress
  • Reversible mental depression and other CNS effects
  • Mesenteric arterial thrombosis, ischemic colitis
  • Skin rashes and dry eyes
  • Erythematous rash

Pregnancy & Lactation

Pregnancy Category D, caution during nursing

Precautions & Warnings

  • Evaluation in patients already on beta blocker
  • Aggravation of peripheral arterial circulatory disorders
  • Caution in patients with impaired renal function

Use in Special Populations

Dosage adjustment in elderly and renal impaired patients

Overdose Effects

Symptoms include lethargy, respiratory disorders, bradycardia

Therapeutic Class

Beta-adrenoceptor blocking drugs, Beta-blockers

Storage Conditions

Use before expiry date, keep out of reach of children, dispensed only on prescription

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