TRD-Contin 100 mg (Tablet)

Unit Price: ৳ 30.10 (5 x 10: ৳ 1,505.00)

Strip Price: ৳ 301.00

Medicine Details

Category	Details
Generic	Tramadol hydrochloride
Company	Mundipharma bd pvt ltd
Also available as	Trd contin 50 mg tablet

Indications

Postoperative pain
Colic and spastic pain
Cancer pain
Joint pain
Neck and back pain
Pain associated with osteoporosis

Pharmacology

Centrally acting synthetic analgesic compound. It inhibits the re uptake of neurotransmitters- serotonin and noradrenaline. It modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in analgesia.

Dosage & Administration

Usual doses 50 to 100 mg every four to six hours
Initial dose for acute pain 100 mg
Total daily dosage by mouth should not exceed 400 mg
Sustained Release Capsule dosage one every 12 hours
Injection dose of 50-100 mg every 4 to 6 hours
Suppository dosage for adults 100 mg Tramadol Hydrochloride 6 hourly

Interaction

Not recommended for combination with monoamine oxidase (MAO) inhibitors. Concomitant administration of carbamazepine causes a significant increase in TRD-Contin metabolism.

Contraindications

Hypersensitivity to Tramadol. Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids or psychotropic drugs.

Side Effects

Dizziness/vertigo
Nausea
Constipation
Headache
Somnolence
Vomiting
Pruritus
CNS stimulation
Asthenia
Sweating
Dyspepsia
Dry mouth
Diarrhoea
Malaise
Allergic reaction
Weight loss
Vasodilatation
Palpitations
Abdominal pain
Anorexia
Flatulence
GI bleeding
Hepatitis
Stomatitis

Pregnancy & Lactation

Safe use in pregnancy not established. Tramadol crosses the placenta. Should not be administered during breastfeeding.

Precautions & Warnings

Respiratory depression
Opioid dependence
Concomitant CNS depressants
Concomitant MAO inhibitors
Caution in patients with increased intracranial pressure or head injury
Caution in patients with acute abdominal conditions

Use in Special Populations

In children from the age of 1 year TRD-Contin can be given in a dose of 1-2 mg/kg body weight. Suppository should not be administered in children and adolescents below the age of 14 years. TRD-Contin 100 mg SR Capsules have not been studied in children.

Therapeutic Class

Opioid analgesics

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.