Tridol 50 mg (Capsule)

Unit Price: ৳ 7.50 (18's pack: ৳ 135.00)

Medicine Details

Category	Details
Generic	Tramadol hydrochloride
Company	Globex pharmaceuticals ltd
Also available as	Tridol 100 mg injection

Indications

Postoperative pain
Colic and spastic pain
Cancer pain
Joint pain
Neck and back pain
Pain associated with osteoporosis

Pharmacology

Tramadol is a centrally acting synthetic analgesic compound that inhibits the reuptake of neurotransmitters serotonin and noradrenaline. It modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in analgesia. The analgesic effects of Tramadol are mediated via stimulation of mu-opioid receptors and indirect modulation of central monoaminergic inhibitory pathways.

Dosage & Administration

Usual doses of 50 to 100 mg every four to six hours
Initial dose of 100 mg for acute pain
Initial dose of 50 mg for chronic painful conditions
Total daily dosage by mouth should not exceed 400 mg

Interaction

Physicians need not be concerned about drugs interacting with Tridol except for monoamine oxidase (MAO) inhibitors.

Contraindications

Hypersensitivity to the drug
Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids, or psychotropic drugs

Side Effects

Dizziness/vertigo
Nausea
Constipation
Headache
Somnolence
Vomiting
Pruritus
CNS stimulation
Asthenia
Sweating
Dyspepsia
Dry mouth
Diarrhoea
Malaise
Allergic reaction
Weight loss
Vasodilatation
Palpitations
Abdominal pain
Anorexia
Flatulence
GI bleeding
Hepatitis
Stomatitis

Pregnancy & Lactation

Safe use of Tramadol in pregnancy has not been established. It should be used during pregnancy only if the potential benefit justifies the risk to the fetus. Tramadol should not be administered during breastfeeding.

Precautions & Warnings

Respiratory depression may result from large doses
Not recommended for patients dependent on opioids
Caution when administering with CNS depressants
Caution when administering with MAO inhibitors
Caution in patients with increased intracranial pressure, head injury, and acute abdominal conditions

Use in Special Populations

Tridol can be given in a dose of 1-2 mg/kg body weight in children from the age of 1 year. However, suppository (100 mg Tridol) should not be administered in children and adolescents below the age of 14 years.

Therapeutic Class

Opioid analgesics

Storage Conditions

Keep below 30°C, away from light and moisture, and out of the reach of children.