Tridol 100 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 20.00 (5's pack: ৳ 100.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tramadol hydrochloride |
| Company | Globex pharmaceuticals ltd |
| Also available as |
Indications
- Moderate to severe painful conditions
- Postoperative pain
- Colic and spastic pain
- Cancer pain
- Joint pain
- Neck and back pain
- Pain associated with osteoporosis
Pharmacology
- Centrally acting synthetic analgesic compound
- Inhibits reuptake of neurotransmitters
- Activates serotonergic pathways
- Activates noradrenergic pathways
- Stimulation of mu-opioid receptors
- Modulation of central monoaminergic pathways
Dosage & Administration
- Capsule or Tablet
- Sustained Release Capsule or Tablet
- Injection
- Suppository
- Usual doses of 50-100 mg every 4-6 hours
- Initial doses of 100 mg for acute pain
- Maximum daily dosage of 400 mg
- Injection dose of 50-100 mg every 4-6 hours
- Suppository dose of 100 mg Tramadol Hydrochloride every 6 hours
Interaction
- Monoamine oxidase (MAO) inhibitors not recommended for combination
- Concomitant administration of carbamazepine increases Tramadol metabolism
Contraindications
- Hypersensitivity to Tramadol
- Acute intoxication with alcohol, hypnotics, opioids, or psychotropic drugs
Side Effects
- Dizziness/vertigo
- Nausea
- Constipation
- Headache
- Somnolence
- Vomiting
- Pruritus
- CNS stimulation
- Asthenia
- Sweating
- Dyspepsia
- Dry mouth
- Diarrhea
- Malaise
- Allergic reaction
- Weight loss
- Vasodilatation
- Palpitations
- Abdominal pain
- Anorexia
- Flatulence
- GI bleeding
- Hepatitis
- Stomatitis
Pregnancy & Lactation
- Tramadol crosses placenta
- Use during pregnancy justified if potential benefit outweighs risk
- Not recommended during breastfeeding
Precautions & Warnings
- Respiratory depression risk
- Not recommended for opioid-dependent patients
- Use with caution with CNS depressants
- Use with great caution with MAO inhibitors
- Caution in patients with increased intracranial pressure or head injury
- Caution in patients with acute abdominal conditions
Use in Special Populations
- Children from the age of 1 year can be given 1-2 mg/kg body weight
- Suppository (100 mg Tramadol) not for children below 14 years
- Tramadol 100 mg SR Capsules not studied in children
Therapeutic Class
- Opioid analgesics
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children