Pyrex T 325 mg+37.5 mg (Tablet)
Unit Price: ৳ 8.02 (3 x 10: ৳ 240.60)
Strip Price: ৳ 80.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol tramadol hydrochloride |
| Company | Concord pharmaceuticals ltd |
Title
- Pyrex T Combination Tablet
Category
- Pain Management
- Analgesic
- Opioid Analgesic
- Antipyretic
Description
- Pyrex T Combination Tablet for managing moderate to moderately severe pain in adults and short-term management of acute pain.
Dosage & Administration
- Dosage: 1 or 2 tablets every 4 to 6 hours for moderate to moderately severe pain. Maximum of 8 tablets per day.
- Dosage: 2 tablets every 4 to 6 hours for short-term management of acute pain. Maximum of 8 tablets per day.
- Can be administered without regard to food.
Contraindications
- Not to be administered to patients with hypersensitivity to tramadol, paracetamol, or opioids.
Pharmacology
- Paracetamol has analgesic, antipyretic properties, weak anti-inflammatory activity. Tramadol is a centrally acting synthetic opioid analgesic.
Mode of Action
- Paracetamol increases pain threshold by inhibiting COX-1, COX-2, COX-3 enzymes. Tramadol binds to μ-opioid receptors and inhibits norepinephrine and serotonin reuptake.
Side Effects
- Adverse reactions may include asthenia, fatigue, dizziness, headache, abdominal pain, constipation, nausea, vomiting, anxiety, insomnia, rash, increased sweating, etc.
Pregnancy & Lactation
- Pregnancy Category C. Use during pregnancy only if benefit justifies potential risk. Not recommended for nursing mothers.
Precautions & Warnings
- May impair mental or physical abilities. Avoid alcohol-containing beverages. Use with caution with other tramadol or paracetamol-containing products. Use with caution when taking tranquilizers, hypnotics, or other opiate-containing analgesics.
Use in Special Populations
- Pediatric use not studied. Caution in geriatric patients. Not studied in renal and hepatic impaired patients.
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place. Do not freeze. Keep out of the reach of children.