Cardisef 50 mg (Tablet)

Unit Price: ৳ 0.77 (100's pack: ৳ 77.00)

Medicine Details

Category Details
Generic Atenolol
Company Supreme pharmaceutical ltd
Also available as

Indications

  • Hypertension management
  • Angina pectoris management
  • Acute myocardial infarction management

Mode of Action

  • Competitive block of beta1 (cardiac) receptors
  • Beta1 selective (cardioselective) beta-adrenergic receptor antagonist
  • No membrane stability activity
  • No partial agonist activity

Dosage & Administration

  • Initial dose of 50mg for hypertension
  • Initial dose of 50mg for angina pectoris
  • Initial intravenous dose in acute myocardial infarction

Interaction

  • Additive effect with catecholamine-depleting drugs
  • Additive effect with calcium channel blockers
  • Potential interaction with disopyramide
  • Potential interaction with amiodarone
  • Exacerbation of rebound hypertension with clonidine
  • Decrease in hypotensive effects with prostaglandin synthase inhibiting drugs
  • Increased severity of anaphylactic reactions
  • Increased risk of bradycardia with digitalis glycosides

Contraindications

  • Sinus bradycardia
  • Cardiogenic shock
  • Overt cardiac failure
  • Hypersensitivity to atenolol or its components

Side Effects

  • Agranulocytosis
  • Allergic reactions
  • Reversible mental depression
  • Mesenteric arterial thrombosis
  • Skin rashes
  • Erythematous rash

Pregnancy & Lactation

  • Pregnancy Category D
  • Caution in nursing women
  • Risk of bradycardia in breast-fed infants

Precautions & Warnings

  • Evaluation of patients already on a beta blocker
  • Aggravation of peripheral arterial circulatory disorders
  • Caution in impaired renal function
  • Caution in geriatric use

Use in Special Populations

  • Adjustment of dosage in renal impairment
  • Cautious dose selection for elderly patients

Overdose Effects

  • Lethargy
  • Respiratory disorder
  • Sinus pause
  • Bradycardia
  • Congestive heart failure
  • Hypotension
  • Bronchospasm
  • Hypoglycemia

Therapeutic Class

  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Expiry date consideration
  • Keep out of reach of children
  • Dispensation with prescription

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