Flunarin 10 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Flunarizine |
| Company | Apex pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis of classic (with aura) or common (without aura) migraine
- Symptomatic treatment of vestibular vertigo (due to a diagnosed functional disorder of the vestibular system)
- Peripheral Vascular Disease (PVD)
- Motion sickness
- Refractory epilepsy resistant to conventional antiepileptic therapy
Pharmacology
- Selective calcium channel antagonist
- Reduces excessive transmembrane influx of calcium
- Binds at an affinity of 99% to plasma protein
- Has antihistaminic and sedative properties
Dosage & Administration
- Starting Dose: 10 mg at night in patients less than 65 years of age and 5 mg daily in patients older than 65 years
- Maintenance Treatment: Decrease to 5 days treatment at the same daily dose with two successive medicine free days every week
- Peripheral Vascular Disease: 10 mg twice daily, up to 30 mg per day if required
- Vertigo & motion sickness: 10-20 mg daily for adults and 5 mg daily for children (> 40 kg)
- Epileptic seizure: 15-20 mg daily in adults and 5 to 10 mg daily for children as an add-on therapy
Interaction
Hepatic enzyme inducers may interact with Flunarin by increasing its metabolism
Contraindications
- Hypersensitivity to Flunarizine
- History of depressive illness
- Pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders
Side Effects
- Drowsiness and/or fatigue
- Weight gain and/or increased appetite
- Depression
- Extrapyramidal symptoms (such as bradykinesia, rigidity, akathisia, orofacial dyskinesia, tremor)
- Heartburn
- Nausea
- Gastralgia
- Insomnia
- Anxiety
- Galactorrhoea
- Dry mouth
- Muscle ache
- Skin rash
Pregnancy & Lactation
Safety not established
Precautions & Warnings
- May lead to drowsiness
- Aggravated by the simultaneous intake of alcohol or other central nervous system depressants
- Not suited for aborting a migraine attack
- Possible occurrence of extrapyramidal and depressive symptoms
- Reveals Parkinsonism, especially in predisposed patients such as the elderly
Therapeutic Class
Miscellaneous prophylactic migraine preparations
Storage Conditions
Keep below 30°C temperature, away from light & moisture