Flurium 10 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Flunarizine |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis of classic (with aura) or common (without aura) migraine
- Symptomatic treatment of vestibular vertigo (due to a diagnosed functional disorder of the vestibular system)
- Peripheral Vascular Disease (PVD)
- Motion sickness
- Refractory epilepsy resistant to conventional antiepileptic therapy
Pharmacology
- Selective calcium channel antagonist
- Reduces excessive transmembrane influx of calcium
- Antihistaminic and sedative properties
- Binds at an affinity of 99% to plasma protein
Dosage & Administration
- Starting dose: 10 mg at night in patients less than 65 years of age and 5 mg daily in patients older than 65 years
- Maintenance treatment: Decrease to 5 days treatment at the same daily dose with two successive medicine free days every week
- Peripheral Vascular disease: 10 mg twice daily, up to 30 mg per day if required
- Vertigo & motion sickness: 10-20 mg daily for adults and 5 mg daily for children
- Epileptic seizure: 15-20 mg daily in adults and 5 to 10 mg daily for children as an add-on therapy
Interaction
Galactorrhoea has been reported in few women on oral contraceptives within the first two months of Flurium treatment. Hepatic enzyme inducers may interact with Flurium by increasing its metabolism, requiring an increase in dosage.
Contraindications
- Hypersensitivity to Flunarizine
- History of depressive illness
- Pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders
Side Effects
- Drowsiness and/or fatigue
- Weight gain and/or increased appetite
- Depression, particularly in female patients with a history of depressive illness
- Extrapyramidal symptoms, particularly in elderly patients
- Heartburn
- Nausea
- Gastralgia
- Insomnia
- Anxiety
- Dry mouth
- Muscle ache
- Skin rash
Pregnancy & Lactation
Safety in pregnancy and lactation has not been established
Precautions & Warnings
- May lead to drowsiness
- Aggravated by the simultaneous intake of alcohol or other central nervous system depressants
- Not suited for aborting a migraine attack
- May give rise to extrapyramidal and depressive symptoms
- Reveals Parkinsonism, especially in predisposed patients such as the elderly
Therapeutic Class
Miscellaneous prophylactic migraine preparations
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children