Imigra 5 mg (Capsule)
Unit Price: ৳ 4.02 (6 x 10: ৳ 241.20)
Strip Price: ৳ 40.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Flunarizine |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis of classic migraine with aura
- Prophylaxis of common migraine without aura
- Symptomatic treatment of vestibular vertigo
- Symptomatic treatment of motion sickness
- Treatment of peripheral vascular disease
- Treatment of refractory epilepsy resistant to conventional therapy
Pharmacology
- Flunarizine is a difluorinated derivative of cinnarizine
- Selective calcium channel antagonist
- Prevents cellular calcium overload
- Has antihistaminic and sedative properties
- Binds at an affinity of 99% to plasma protein
Dosage & Administration
- Starting dose of 10 mg at night in patients less than 65 years of age
- Starting dose of 5 mg daily in patients older than 65 years
- Maintenance treatment with decreased dose and medicine-free days
- Peripheral vascular disease dosage: 10 mg twice daily, up to 30 mg/day
- Vertigo & motion sickness dosage: 10-20 mg daily for adults
- Vertigo & motion sickness dosage: 5 mg daily for children (> 40 kg)
- Epileptic seizure dosage: 15-20 mg daily in adults
- Epileptic seizure dosage: 5-10 mg daily for children as add-on therapy
Interaction
- Galactorrhoea reported in few women on oral contraceptives with Imigra treatment
- Hepatic enzyme inducers may interact with Imigra by increasing its metabolism
Contraindications
- Hypersensitivity to Flunarizine
- Contra-indicated in patients with a history of depressive illness
- Contra-indicated in patients with pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders
Side Effects
- Drowsiness and/or fatigue
- Weight gain and/or increased appetite
- Adverse experiences: depression, extrapyramidal symptoms, heartburn, nausea, etc.
Pregnancy & Lactation
- Safety not established in pregnancy and lactation
Precautions & Warnings
- May lead to drowsiness aggravated by alcohol or CNS depressants
- Caution against driving or performing hazardous tasks
- Not suited for aborting a migraine attack
- May give rise to extrapyramidal and depressive symptoms and reveal Parkinsonism
Therapeutic Class
- Miscellaneous prophylactic migraine preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children