Carsec 100 mg (Tablet)
Unit Price: ৳ 1.35 (140's pack: ৳ 189.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atenolol |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Management of hypertension
- Long-term management of patients with angina pectoris
- Management of hemodynamically stable patients with acute myocardial infarction
Pharmacology
- Beta1 selective (cardioselective) beta-adrenergic receptor antagonist
- Hydrophilic nature
Dosage & Administration
- Initial dose of 50mg for hypertension
- Initial dose of 50mg for angina pectoris
- Intravenous administration for acute myocardial infarction
Interaction
- Additive effect with catecholamine-depleting drugs
- Additive effect with calcium channel blockers
- Interaction with disopyramide and amiodarone
- Exacerbation of rebound hypertension with clonidine withdrawal
- Decreased hypotensive effects with prostaglandin synthase inhibiting drugs
- Increased severity of allergic reaction in patients with beta blockers
- Potential risk of bradycardia when used with digitalis glycosides
Contraindications
- Sinus bradycardia
- Heart block greater than first degree
- Cardiogenic shock
- Overt cardiac failure
- History of hypersensitivity to atenolol or its components
Side Effects
- Agranulocytosis
- Fever combined with aching and sore throat
- Reversible mental depression
- Mesenteric arterial thrombosis
- Skin rashes
- Dry eyes
- Erythematous rash
Pregnancy & Lactation
- Pregnancy Category D
- Caution in nursing women
- Risk of bradycardia in breast-fed infants
- Potential adverse effects in premature infants and those with impaired renal function
Precautions & Warnings
- Evaluation of patients already on beta blockers
- Adjustment of dosage based on clinical observations
- Aggravation of peripheral arterial circulatory disorders
- Caution in patients with impaired renal function
- Dose selection for elderly patients
- Assessment of renal function in hypertension and myocardial infarction patients
Use in Special Populations
- Dosage adjustment for elderly and renal-impaired patients
- Maximum oral dosages based on creatinine clearance
- Lower starting dose for some renal impaired or elderly patients
- Caution in patients on hemodialysis
Overdose Effects
- Reported overdoses surviving acute doses as high as 5g
- Expected symptoms including lethargy, respiratory disorder, bradycardia, hypotension, bronchospasm, and hypoglycemia
- Directions for overdose treatment including induced emesis, gastric lavage, activated charcoal, and hemodialysis
- Requirement for intensive support care and facilities for cardiac and respiratory support
Therapeutic Class
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Expiry date
- Keep out of reach of children
- Dispense only on prescription of a registered physician