Inflam-D 400 mg (Tablet)
Unit Price: ৳ 5.04 (5 x 10: ৳ 252.00)
Strip Price: ৳ 50.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexibuprofen |
| Company | Synovia pharma plc |
| Also available as |
Indications
- Relief of signs and symptoms of osteoarthritis
- Rheumatoidal disorders treatment
- Acute symptomatic treatment of painful menstruation
- Treatment of common headache and fever
- Symptomatic treatment of mild to moderate pain
- Adjuvant with common cold and influenza associated with headache
Pharmacology
- Dexibuprofen is the pharmacologically active enantiomer of racemic ibuprofen
- Non-steroidal anti-inflammatory drug
- Analgesic action
- Inhibits prostaglandin synthesis
- Absorbed primarily from the small intestine
- Metabolic transformation in the liver
- Completely excreted mainly by the kidneys
Dosage & Administration
- Dosage adjusted to the seriousness of the syndrome and patient's complaints
- Recommended dosage: 600-900 mg Dexibuprofen per day, at 2-3 divided doses
- Maximum daily dose is 1200 mg
- Dosage for dysmenorrhea: 600-900 mg per day
Interaction
- Simultaneous use of anticoagulant, hydantoine and sulfonamide, ticlopidine, lithium, other NSAID's, ACE inhibitors, beta blockers, cyclosporine
- Interactions with tacrolimus, corticosteroids, digoxin, methotrexate, pentoxyfiline, phenytoine, probenecid, sulfinpyrazon, sulfonylurea, thiazide and thiazide type diuretics, zidovudine
Contraindications
- Hypersensitivity to Dexibuprofen or other NSAID
- Previous attack of asthma, bronchospasm, acute rhinitis, urticaria or edema after use of similar drugs
- Active or suspected hemorrhage
- Crohn's disease or ulcerative colitis
- Serious heart diseases
- Kidney function impairment (GFR <30ml/min)
- Liver function impairment
Side Effects
- Dyspepsia
- Diarrhea
- Fatigue
- Headache
- Nausea
- Vomiting
- Abdominal pain
- Hypersensitivity reactions
- Bleeding
- Ulcer
Pregnancy & Lactation
- Avoid use during pregnancy
- Avoid use during late pregnancy
- Use with caution in nursing mothers
Precautions & Warnings
- Caution in patients with bronchial asthma or other chronic pulmonary diseases
- Caution in patients with hepatic, renal or cardiac insufficiency
- Consultation with a doctor for patients with systemic lupus or other autoimmunological disease
- Caution in active and suspected hemorrhagic conditions such as gastro-duodenal ulcers, ulcerative colitis, Crohn's disease, alcoholism
Use in Special Populations
- Caution in patients with hepatic impairment
- Caution in patients with renal impairment
- Children dosage
- Dosage for elderly people
Overdose Effects
- Low acute toxicities
- Symptoms occur at doses between 80 and 100 mg/kg body weight
- Treatment must be symptomatic
- No specific antidote
- Activated charcoal administration for large quantities
- Vomiting induction if life-threatening quantities ingested within 60 minutes
- Little value of dialysis and hemodialysis as Inflam-D binds strongly to plasma protein
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children