Purifen 100 mg/5 ml (Oral Suspension)

100 ml bottle: ৳ 60.00

Medicine Details

Category	Details
Generic	Dexibuprofen
Company	Incepta pharmaceuticals ltd
Also available as	Purifen 300 mg tablet Purifen 200 mg tablet Purifen 400 mg tablet

Indications

Relief of signs and symptoms of osteoarthritis
Treatment of rheumatoidal disorders
Acute symptomatic treatment of painful menstruation
Treatment of common headache and fever
Symptomatic treatment of mild to moderate pain
Adjuvant with common cold and influenza associated with headache

Pharmacology

Dexibuprofen is the pharmacologically active enantiomer of racemic ibuprofen, a non-steroidal anti-inflammatory drug with analgesic action, acting by inhibiting prostaglandin synthesis.

Dosage & Administration

Recommended dosage of 600-900 mg Dexibuprofen per day
Maximum daily dose of 1200 mg
Specific dosage for dysmenorrhea

Interaction

Reported drug interactions include anticoagulant, hydantoine, sulfonamide, ticlopidine, lithium, other NSAID's, ACE inhibitors, beta blockers, cyclosporine, tacrolimus, corticosteroids, digoxin, methotrexate, pentoxyfiline, phenytoine, probenecid, sulfinpyrazon, sulfonylurea, thiazide and thiazide type diuretics, and zidovudine.

Contraindications

Hypersensitivity to Dexibuprofen or other NSAIDs
History of asthma, bronchospasm, acute rhinitis, urticaria, or edema
Active or suspected hemorrhage, Crohn's disease, ulcerative colitis, serious heart diseases, kidney function impairment, and liver function impairment

Side Effects

Dyspepsia
Diarrhea
Fatigue
Headache
Nausea
Vomiting
Abdominal pain
Hypersensitivity reactions
Bleeding
Ulcer

Pregnancy & Lactation

Avoid use during pregnancy due to known effects on fetal cardiovascular system
Use with caution in nursing mothers

Precautions & Warnings

Use with caution in patients with bronchial asthma or chronic pulmonary diseases
Caution in patients with hepatic, renal, or cardiac insufficiency, and hypertension
Consultation recommended for patients with systemic lupus or other autoimmunological disease
Extreme caution in hemorrhagic conditions and for first-time users

Use in Special Populations

Caution in hepatic, renal, and cardiac insufficiency
Limited use in children under 18 years
Reduced start amount for patients with mild to moderate impairments

Overdose Effects

Low acute toxicities
Symptoms occur at doses between 80 and 100 mg/kg body weight
Treatment should be symptomatic with no specific antidote
Activated charcoal and induced vomiting in case of large quantities
Dialysis of little value as Dexibuprofen binds strongly to plasma proteins