Serifen 300 mg (Tablet)
Unit Price: ৳ 4.02 (5 x 10: ৳ 201.00)
Strip Price: ৳ 40.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexibuprofen |
| Company | Silva pharmaceuticals ltd |
| Also available as |
Indications
- Relief of sign and symptoms of osteoarthritis
- Rheumatoidal disorders
- Acute symptomatic treatment of painful menstruation
- Common headache and fever
- Symptomatic treatment of mild to moderate pain
- Adjuvant with common cold and influenza
Pharmacology
- Non-steroidal anti-inflammatory drug
- Analgesic action
- Inhibiting prostaglandin synthesis
- Absorbed primarily from the small intestine
- Metabolic transformation in the liver
- Plasma protein binding
Dosage & Administration
- Dosage adjustment to seriousness of the syndrome
- Lowest effective dose for chronic pain
- Recommended dosage: 600-900 mg Dexibuprofen per day
- Maximum daily dose: 1200 mg
- Dysmenorrhea dosage: 600-900 mg per day
Interaction
- Simultaneous use of anticoagulant, hydantoine and sulfonamide
- Ticlopidine, lithium, other NSAID's
- ACE inhibitors, beta blockers, cyclosporine, tacrolimus
- Corticosteroids, digoxin, methotrexate, pentoxyfiline
- Phenytoine, probenecid, sulfinpyrazon, sulfonylurea
- Thiazide and thiazide type diuretics, zidovudine
Contraindications
- Hypersensitivity to Dexibuprofen or another NSAID
- Previous experience of asthma, bronchospasm
- Acute rhinitis, urticaria, edema
- Active or suspected hemorrhage
- Crohn's disease or ulcerative colitis
- Serious heart diseases, kidney function impairment
- Liver function impairment
Side Effects
- Dyspepsia
- Diarrhea
- Fatigue
- Headache
- Nausea
- Vomiting
- Abdominal pain
- Hypersensitivity reactions
Pregnancy & Lactation
- Teratogenic impact avoidance during pregnancy
- Avoid use during late pregnancy
- Nonsteroidal anti-inflammatory drugs effects on fetal cardiovascular system
- Caution in nursing mothers
Precautions & Warnings
- Caution in patients with bronchial asthma
- Chronic diseases of the pulmonary tract
- Persons prone to allergy
- Hepatic, renal or cardiac insufficiency
- Hypertension not responding to treatment
- Consultation for patients with systemic lupus or autoimmunological disease
- Cautions in gastro-duodenal ulcers, ulcerative colitis, Crohn's disease, alcoholism
Use in Special Populations
- Caution in patients with mild to moderate liver function impairments
- Avoid use in serious liver function impairments
- Start with reduced amount in mild to moderate kidney function impairments
- Avoid in serious kidney function impairments
- Possible use in children under specific circumstances
- Lowest effective dose for elderly people
Overdose Effects
- Low acute toxicity
- Toxicity symptoms occur at specific doses
- Symptomatic treatment
- Activated charcoal administration
- Induced vomiting in life-threatening situations
- Limited value of dialysis and hemodialysis
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children