Purifen 200 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexibuprofen |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Relief of signs and symptoms of osteoarthritis
- Rheumatoidal disorders treatment
- Acute symptomatic treatment of painful menstruation
- Treatment of common headache and fever
- Symptomatic treatment of mild to moderate pain
- Adjuvant with common cold and influenza associated with headache
Pharmacology
Dexibuprofen is a non-steroidal anti-inflammatory drug with analgesic action, acts by inhibiting prostaglandin synthesis, absorbed primarily from the small intestine, elimination half-life is 1.8-3.5 hours.
Dosage & Administration
Recommended dosage is 600-900 mg Dexibuprofen per day, can be raised temporarily up to 1200 mg per day, at a divided dose.
Interaction
Drug interactions with anticoagulant, hydantoine, sulfonamide, ticlopidine, lithium, other NSAIDs, ACE inhibitors, beta blockers, cyclosporine, tacrolimus, corticosteroids, digoxin, methotrexate, pentoxyfiline, phenytoine, probenecid, sulfinpyrazon, sulfonylurea, thiazide and thiazide type diuretics, zidovudine.
Contraindications
- Hypersensitivity to Dexibuprofen
- Previous history of hypersensitivity to NSAID
- Active or suspected hemorrhage
- Serious heart diseases
- Kidney function impairment
- Liver function impairment
Side Effects
- Dyspepsia
- Diarrhea
- Fatigue
- Headache
- Nausea
- Vomiting
- Abdominal pain
- Hypersensitivity reactions
- Bleeding
- Ulcer
Pregnancy & Lactation
- Avoid use during pregnancy
- Avoid use during late pregnancy
- Use with caution in nursing mothers
Precautions & Warnings
Use with caution in patients with bronchial asthma, chronic pulmonary diseases, hepatic, renal or cardiac insufficiency, hypertension, autoimmune diseases, hemorrhagic conditions.
Use in Special Populations
- Hepatic impairment
- Renal impairment
- Children Dose
- Elderly people dosage recommendation
Overdose Effects
Low acute toxicities, treatment must be symptomatic, no specific antidote, activated charcoal administration, vomiting induction only when life-threatening quantities ingested, dialysis of little value.
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Do not store above 30°C, keep away from light and out of the reach of children