Norpress 50 mg (Tablet)

Unit Price: ৳ 0.75 (100's pack: ৳ 75.00)

Medicine Details

Category Details
Generic Atenolol
Company Kemiko pharmaceuticals ltd
Also available as

Title

  • Norpress

Categories

  • Hypertension Medicine
  • Heart Medication
  • Beta-adrenoceptor blocking drugs

Description

  • Norpress is a beta-adrenoceptor antagonist used in the management of hypertension, long-term management of angina pectoris, and in hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce cardiovascular mortality.

Dimensions

  • Standard tablet size

Color Options

  • None

Functions

  • Manages hypertension
  • Treatment for angina pectoris
  • Reduces cardiovascular mortality in acute myocardial infarction patients

Materials

  • Active ingredient: Atenolol
  • May include inactive ingredients such as cellulose, silicon dioxide, and magnesium stearate

Dosage

  • Initial dose: 50mg once a day
  • May be increased to 100mg once a day if necessary
  • Different dosage for hypertension, angina pectoris, and acute myocardial infarction

Mode of Action

  • Competitively blocks β1 (cardiac) receptors
  • β1 selective (cardioselective) β-adrenergic receptor antagonist with no membranestability activity and no partial agonist activity

Usability Features

  • Once-daily dosing for 24-hour control
  • Available as tablets for oral administration
  • Initial intravenous dose for acute myocardial infarction patients

Interactions

  • Possible additive effect with catecholamine-depleting drugs
  • Additive effect with calcium channel blockers
  • Caution with concomitant use of prostaglandin synthase inhibiting drugs

Contraindications

  • Sinus bradycardia
  • Heart block greater than first degree
  • Cardiogenic shock
  • Overt cardiac failure
  • History of hypersensitivity to atenolol or any of the drug product’s components

Side Effects

  • Bradycardia
  • Hypotension
  • Agranulocytosis
  • Allergic reactions like fever and respiratory distress
  • Central nervous system effects like reversible mental depression and short-term memory loss

Pregnancy & Lactation

  • Pregnancy Category D
  • Clinically significant bradycardia reported in breast-fed infants

Precautions & Warnings

  • Caution in patients with impaired renal function
  • Evaluation of elderly patients before administration
  • May aggravate peripheral arterial circulatory disorders

Special Populations

  • Dosage adjustment for elderly patients or patients with renal impairment
  • Maximum recommended oral dosages for patients with impaired renal function

Overdose Effects

  • Overdosage may lead to lethargy, disorder of respiratory drive, wheezing, sinus pause, and bradycardia
  • Treatment may require intensive support care and facilities for applying cardiac and respiratory support

Therapeutic Class

  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Do not use later than the date of expiry
  • Keep out of reach of children
  • To be dispensed only on the prescription of a registered physician

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