A-Fenac 12.5 mg (Suppository)
Unit Price: ৳ 9.00 (2 x 5: ৳ 90.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- As pre-operative medication for the prevention of pain, inflammation, and swelling
- Post-operative and post-traumatic pain
- Prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract
- Renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Pronounced anti-rheumatic properties
- Anti-inflammatory
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- Metabolized in the liver
Dosage & Administration
- Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food
- Dose should be reduced in long term use
- Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses
- Elderly patients: Lowest effective dosage recommended
- Maximum daily dose: 150 mg
- Dosage depends on the form of the tablet/capsule/gel/suppository/injection
Interaction
- May interact with lithium and digoxin
- Risk of haemorrhage with anticoagulant therapy
- Can be given together with oral antidiabetic agents
- Cases of nephrotoxicity with cyclosporin
- Serious toxicity when used with methotrexate
- Potential convulsions with quinolone antimicrobials
- Increased frequency of unwanted effects with other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
- Contra-indicated in asthmatic patients with triggered attacks
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Should be used only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
- Close observation for advanced age patients
- Avoid contact with eyes or mucus membranes
- Proper hand washing after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children