Alterin TR 100 mg (Capsule (Timed Release))
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Euro pharma ltd |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive conditions
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Preoperative medication for pain prevention
- Prevention of inflammation and swelling post-surgery
- Post-traumatic pain relief
- Pain and inflammation prevention for urogenital tract operation patients
- Pain and inflammation treatment for renal and biliary colic patients
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic properties
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from gastrointestinal tract
- Peak plasma concentrations reached in 2 hours
- 99.7% bound to plasma proteins
- Metabolized in the liver
- Undergoes first pass metabolism
Dosage & Administration
- Diclofenac FC Tablet: 75-150 mg daily in 2 to 3 divided doses
- Diclofenac SR Tablet: 1 tablet daily for adults, 1-3 mg/kg body weight for children
- Diclofenac Dispersible Tablet: 2-3 tablets daily for adults, 1-3 mg/kg body weight for children
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository: 50 mg 2-3 times daily for adults
- Diclofenac injection: 1 ampoule daily for adults, up to 2 ampoules daily in serious cases
- Diclofenac Gel: Applied 3-4 times daily to affected area
Interaction
- May increase plasma concentrations of lithium and digoxin
- Increased risk of hemorrhage with combined use of anticoagulants
- Can be given together with oral antidiabetic agents
- Cases of nephrotoxicity with concurrent cyclosporin use
- Serious toxicity reported with concurrent use of methotrexate
- Caution required with concomitant therapy of NSAID and quinolones
- Increased frequency of unwanted effects with co-administration of other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroidal anti-inflammatory agents
- Contra-indicated in asthmatic patients with specific precipitated conditions
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Close observation in advanced age patients
- Avoid contact with eyes or mucous membranes
- Proper hand washing after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protect from light
- Store below 30°C
- Keep out of the reach of children