Anodyne 50 mg (Tablet)
Unit Price: ৳ 1.00 (10 x 10: ৳ 100.00)
Strip Price: ৳ 10.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Inflammatory and degenerative rheumatism
- Chronic involutive polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for pain and swelling prevention
- Post-operative pain relief
- Post-traumatic pain relief
- Pain and inflammation prevention in urogenital tract
- Renal and biliary colic treatment
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from gastro-intestinal tract
- Metabolized in the liver
- First pass metabolism
Dosage & Administration
- Adult dosage of 75-150 mg daily
- Divided doses
- After food consumption
- Usage in children
- Elderly patient dosage recommendation
- Supplementation with conventional tablets
- Maximum daily dosage
- Suppository administration
- External use gel application instructions
Interaction
- Increased plasma concentrations of lithium and digoxin
- Potential increased risk of haemorrhage with anticoagulant therapy
- Ability to be given together with oral antidiabetic agents
- Potential nephrotoxicity when combined with cyclosporin
- Reported cases of serious toxicity when combined with methotrexate
- Potential convulsions with quinolone antimicrobials
- Increased frequency of unwanted effects with other NSAIDs and steroids
- Lowering of plasma levels with aspirin
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
- Contraindicated in asthmatic patients and those with precipitated attacks
Side Effects
- Mild, rare and transient adverse effects
- Possibility of epigastric pain, eructation, nausea, diarrhea, dizziness, headache
- Encountered peripheral edema and skin reactions
- Local skin irritation and reddening with gel application
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose recommended
- Not recommended during first trimester
- Not recommended during lactation due to insignificant quantity detected in breast milk
Precautions & Warnings
- Close observation in instances of peptic ulceration or gastrointestinal bleeding
- Increased caution in advanced age patients
- Avoid contact with eyes or mucus membranes
- Proper hand washing after application
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children