Anodyne 1% w/w (Gel)

20 gm tube: ৳ 40.00

Medicine Details

Category Details
Generic Diclofenac sodium
Company Ibn sina pharmaceuticals ltd
Also available as
Anodyne 50 mg tablet Anodyne sr 100 mg capsule Volicool 1 w gel

Title

Anodyne Gel

Categories

  • Pain Relief
  • Anti-inflammatory
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)
  • Topical Medication

Description

Anodyne Gel is a potent non-steroidal anti-inflammatory gel used for the relief of pain and inflammation associated with rheumatism, osteoarthritis, gout, trauma, and post-operative procedures. It is indicated for various medical specialties including rheumatology, surgery, traumatology, obstetrics, gynecology, otorhinolaryngology, dentistry, and urogenital procedures.

Formulation

  • Gel

Indications

  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive, polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Post-operative pain and inflammation
  • Mastitis
  • Pre-operative medication for the prevention of pain, inflammation, and swelling

Mode of Action

Potent non-steroidal anti-inflammatory drug with pronounced anti-rheumatic, analgesic, and antipyretic properties. Inhibits prostaglandin biosynthesis to alleviate inflammation, pain, and fever. Rapid and complete absorption from the gastrointestinal tract.

Dosage & Administration

  • Adults: 75-150 mg daily in 2 to 3 divided doses
  • Diclofenac SR Tablet for adults: 1 tablet daily, increased to 150 mg if necessary
  • Diclofenac Dispersible Tablet for adults: 2-3 tablets daily, maximum 150 mg
  • Diclofenac TR Capsule: One capsule daily
  • Diclofenac Suppository for adults: 50 mg 2-3 times daily, maximum 150 mg
  • Diclofenac injection: 1 ampoule daily, up to 2 ampoules in serious cases
  • Diclofenac Gel: Apply 2-4 g to the affected area 3-4 times daily

Interaction

  • Increased plasma concentrations of lithium and digoxin
  • Isolated reports of increased risk of hemorrhage with anticoagulant therapy
  • Clinical studies showing no influence on antidiabetic agents
  • Cases of nephrotoxicity with concurrent use of cyclosporin
  • Serious toxicity reported with concurrent use of methotrexate and NSAIDs
  • Potential convulsions due to interaction between quinolone antimicrobials and NSAIDs
  • Increased frequency of unwanted effects with co-administration of other systemic NSAIDs and steroids

Contraindications

  • Hypersensitivity to any ingredient
  • Peptic ulcer
  • Hypersensitivity to Diclofenac
  • Asthmatic patients prone to attacks precipitated by prostaglandin synthetase inhibitor drugs

Side Effects

  • Mild, rare and transient adverse effects
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions such as rash and eczema
  • Local irritation and reddening of the skin

Pregnancy & Lactation

Use only for compelling reasons during pregnancy, lowest effective dose should be used. Not recommended during the first trimester. Insignificant quantity detected in breast milk with no expected effects on the infant.

Precautions & Warnings

  • Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
  • Avoid contact with eyes or mucus membranes
  • Properly wash hands after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store in a cool and dry place below 30°C, protected from light. Keep out of the reach of children.

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