Apain Plus (75 mg+20 mg)/2 ml (IM Injection)
2 ml ampoule: ৳ 15.05 (10's pack: ৳ 150.50)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium lidocaine hydrochloride |
| Company | Kemiko pharmaceuticals ltd |
Indications
- Relief of pain
- Relief of inflammation
- Arthritic conditions
- Acute musculoskeletal disorders
- Periarthritis
- Tendinitis
- Bursitis
- Trauma-related pain
- Orthopaedic surgeries
- Dental surgeries
- Renal colic
- Local anaesthetic effect
- Minimization of injection site pain
Pharmacology
- Potent nonsteroidal antiinflammatory drug
- Analgesic properties
- Antipyretic properties
- Uricosuric effects
- Inhibition of prostaglandin synthesis
- Peak plasma concentration
- Rapid action of Lidocaine
- Stability of Lidocaine
- Surface anaesthetic effect
- Impairment of nerve impulses
Dosage & Administration
- Adult dosage
- Renal colic dosage
- Children dosage
- Elderly patients dosage
Interaction
- Interaction with Lithium and Digoxin
- Interaction with anticoagulants
- Interaction with antidiabetic agents
- Interaction with Cyclosporin
- Interaction with Methotrexate
- Interaction with quinolone antimicrobials
- Interaction with other NSAIDs and steroids
- Interaction with diuretics
Contraindications
- Hypersensitivity to Diclofenac
- Peptic ulcer or gastrointestinal bleeding
- Asthma, urticaria or acute rhinitis induced by Aspirin or NSAIDs
- Hypersensitivity to Lidocaine
- Adams-Stokes syndrome
- SA, AV, or intraventricular heart block
- Hypersensitivity to excipients
Side Effects
- Gastrointestinal discomfort
- Nausea
- Diarrhea
- Bleeding
- Injection site disorder
- Abscesses
- Local necrosis
- CNS adverse effects
- Drowsiness
- Dizziness
- Disorientation
Pregnancy & Lactation Precautions
- Avoidance during pregnancy
- Lowest effective dosage usage
- Avoidance during last trimester of pregnancy
- Detection in breast milk
- No adverse effects on infant
Precautions & Warnings
- Close observation for severe hepatic, cardiac, or renal insufficiency
- Renal function monitoring
- Lowest effective dosage usage for elderly
- Hepatic function monitoring
- Long term treatment monitoring
- Eosinophilia
- Rash manifestation
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Temperature not exceeding 30°C
- Dry place storage
- Protected from light