Clofen TR 100 mg (Capsule (Timed Release))
Unit Price: ৳ 3.08 (50's pack: ৳ 154.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Cosmic pharma ltd |
Indications
- Rheumatology
- Surgery and Traumatology
- Obstetrics and Gynecology
- Otorhinolaryngology
- Dentistry
- Urogenital Tract
- Renal and Biliary Colic
Pharmacology
- Non-steroidal Anti-inflammatory Drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibits Prostaglandin Biosynthesis
- Metabolized in the Liver
Dosage and administration
- Adult Dosage: 75-150 mg daily
- Children Dosage: 1-3 mg of diclofenac/kg body weight daily
- Elderly Patient Dosage: Lowest effective dosage recommended
- Dosage may vary based on tablet type (FC, SR, Dispersible, TR), Suppository, Injection, Gel
- Dosage should be reduced in long term use
Interaction
- May interact with Lithium and Digoxin
- Increased risk of hemorrhage with anticoagulants
- Can be given with oral antidiabetic agents without influencing their clinical effect
- Cases of nephrotoxicity reported with Cyclosporin
- Serious toxicity reported when combined with Methotrexate within 24 hours
- Caution required with quinolone antimicrobials
- Co-administration with other NSAIDs and steroids may increase unwanted effects
- Plasma levels of aspirin reduced when co-administered
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Asthmatic patients sensitive to acetylsalicylic acid or prostaglandin synthetase inhibitor
- Avoid use under occlusive airtight dressings
Side effects
- Mild, rare, and transient adverse effects
- Epigastric pain, eructation, nausea, diarrhea, dizziness, headache
- Peripheral edema, rash, eczema
- Local irritation and reddening of the skin from Gel
Pregnancy and lactation
- Employ only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during first trimester of pregnancy
- Insufficient clinical data for use during pregnancy
- Insignificant quantity may be detected in breast milk
Precautions and warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Caution with advanced age
- Avoid contact with eyes or mucus membranes for Gel application
- No contact with mucus membranes after application
- Not to be taken by mouth
Therapeutic class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage conditions
- Store in a cool and dry place
- Protect from light
- Keep below 30°C
- Keep out of reach of children