Clofenac 12.5 mg (Suppository)

Unit Price: ৳ 12.00 (2 x 5: ৳ 120.00)

Medicine Details

Indications

  • Inflammatory rheumatism
  • Degenerative rheumatism
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Sprains
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for pain prevention
  • Post-operative pain treatment
  • Post-traumatic pain treatment
  • Pain prevention for urogenital tract operations
  • Treatment of inflammation and swelling for urogenital tract operations
  • Renal colic treatment
  • Biliary colic treatment

Pharmacology

  • NSAID
  • Anti-rheumatic properties
  • Anti-inflammatory properties
  • Analgesic properties
  • Antipyretic properties
  • Uricosuric effect
  • Inhibition of prostaglandin biosynthesis
  • Rapid absorption from gastrointestinal tract
  • High plasma protein binding
  • Liver metabolism
  • First pass metabolism

Dosage & Administration

  • Adult dosage: 75-150 mg daily in divided doses
  • Elderly patient dosage
  • Children dosage
  • Maximum daily dose: 150 mg
  • Diclofenac SR Tablet usage
  • Diclofenac Dispersible Tablet usage
  • Diclofenac TR Capsule usage
  • Diclofenac Suppository usage
  • Diclofenac injection dosage
  • Diclofenac Gel application

Interaction

  • Interactions with lithium and digoxin
  • Interactions with anticoagulants
  • Interactions with antidiabetic agents
  • Interactions with cyclosporin
  • Interactions with methotrexate
  • Interactions with quinolone antimicrobials
  • Interactions with other NSAIDs and steroids

Contraindications

  • Hypersensitivity to any ingredient
  • Peptic ulcer
  • Hypersensitivity to NSAIDs
  • Contra-indicated in asthmatic patient
  • Contraindicated under occlusive dressings

Side Effects

  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions
  • Skin rash
  • Local irritation
  • Reddening of skin

Pregnancy & Lactation

  • Use during compelling reasons in pregnancy
  • Lowest effective dose in pregnancy
  • Not recommended in first trimester of pregnancy
  • Not recommended during lactation

Precautions & Warnings

  • Close observation for peptic ulceration
  • Close observation for gastrointestinal bleeding
  • Close observation for advanced age patients
  • Avoid contact with eyes or mucus membranes
  • Hands should be washed after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Cool and dry storage
  • Protected from light
  • Temperature below 30°C
  • Keep out of reach of children

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