Clofenac 12.5 mg (Suppository)

Unit Price: ৳ 12.00 (2 x 5: ৳ 120.00)

Medicine Details

Category Details
Generic Diclofenac sodium
Company Square pharmaceuticals plc
Also available as
Clofenac 50 mg tablet Clofenac sr 100 mg tablet Clofenac 25 mg suppository Clofenac 50 mg suppository Clofenac 1 w gel Clofenac dt 465 mg tablet

Indications

  • Inflammatory rheumatism
  • Degenerative rheumatism
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Sprains
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for pain prevention
  • Post-operative pain treatment
  • Post-traumatic pain treatment
  • Pain prevention for urogenital tract operations
  • Treatment of inflammation and swelling for urogenital tract operations
  • Renal colic treatment
  • Biliary colic treatment

Pharmacology

  • NSAID
  • Anti-rheumatic properties
  • Anti-inflammatory properties
  • Analgesic properties
  • Antipyretic properties
  • Uricosuric effect
  • Inhibition of prostaglandin biosynthesis
  • Rapid absorption from gastrointestinal tract
  • High plasma protein binding
  • Liver metabolism
  • First pass metabolism

Dosage & Administration

  • Adult dosage: 75-150 mg daily in divided doses
  • Elderly patient dosage
  • Children dosage
  • Maximum daily dose: 150 mg
  • Diclofenac SR Tablet usage
  • Diclofenac Dispersible Tablet usage
  • Diclofenac TR Capsule usage
  • Diclofenac Suppository usage
  • Diclofenac injection dosage
  • Diclofenac Gel application

Interaction

  • Interactions with lithium and digoxin
  • Interactions with anticoagulants
  • Interactions with antidiabetic agents
  • Interactions with cyclosporin
  • Interactions with methotrexate
  • Interactions with quinolone antimicrobials
  • Interactions with other NSAIDs and steroids

Contraindications

  • Hypersensitivity to any ingredient
  • Peptic ulcer
  • Hypersensitivity to NSAIDs
  • Contra-indicated in asthmatic patient
  • Contraindicated under occlusive dressings

Side Effects

  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions
  • Skin rash
  • Local irritation
  • Reddening of skin

Pregnancy & Lactation

  • Use during compelling reasons in pregnancy
  • Lowest effective dose in pregnancy
  • Not recommended in first trimester of pregnancy
  • Not recommended during lactation

Precautions & Warnings

  • Close observation for peptic ulceration
  • Close observation for gastrointestinal bleeding
  • Close observation for advanced age patients
  • Avoid contact with eyes or mucus membranes
  • Hands should be washed after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Cool and dry storage
  • Protected from light
  • Temperature below 30°C
  • Keep out of reach of children

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