Clofenac 50 mg (Suppository)
Unit Price: ৳ 20.00 (4 x 5: ৳ 400.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive polyarthritis
- Sprain
- Episiotomy
- As pre-operative medication for the prevention of pain, inflammation, and swelling
- Post-operative and post-traumatic pain
Pharmacology
- Potent non-steroidal anti-inflammatory drug
- Pronounced anti-rheumatic properties
- Analgesic and antipyretic properties
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
Dosage & Administration
- Adults: 75-150 mg daily in 2 to 3 divided doses
- Children: 1-3 mg of diclofenac/kg body weight daily in divided doses
- Elderly patients: Lowest effective dosage is recommended
- External use: 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily
Interaction
- May increase plasma concentrations of lithium and digoxin
- Anticoagulants: Increased risk of haemorrhage
- Cyclosporin: Cases of nephrotoxicity reported
- Methotrexate: Cases of serious toxicity reported when given with NSAIDs
- Quinolone antimicrobials: Caution advised for concomitant therapy with NSAID
Contraindications
- Hypersensitivity to any ingredient of the products
- Peptic ulcer
- Hypersensitivity to Diclofenac
- Asthmatic patient with precipitated attacks by acetylsalicylic acid or other prostaglandin synthetase inhibitors
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain, eructation, nausea, diarrhea, dizziness, headache
- Peripheral edema, skin reactions such as rash and eczema
- Local irritation and reddening of the skin caused by Gel
Pregnancy & Lactation
- Used only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during first trimester of pregnancy
- Not recommended for lactating mothers due to insufficient clinical data
Precautions & Warnings
- Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
- Avoid contact with eyes or mucus membranes
- Keep out of reach of children
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children