Cosfenac SR 100 mg (Capsule (Sustained Release))

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00

Medicine Details

Category Details
Generic Diclofenac sodium
Company Cosmo pharma laboratories ltd

Title

  • Diclofenac FC Tablet
  • Diclofenac SR Tablet
  • Diclofenac Dispersible Tablet
  • Diclofenac TR Capsule
  • Diclofenac Suppository
  • Diclofenac injection
  • Diclofenac Gel

Categories

  • Rheumatology
  • Surgery and Traumatology
  • Obstetrics and Gynecology
  • Otorhinolaryngology
  • Dentistry
  • Other indications

Indications

  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for the prevention of pain, inflammation, and swelling
  • Post-operative and post-traumatic pain, inflammation, and swelling
  • For the prevention of pain and treatment of inflammation and swelling of patients in the urogenital tract, renal and biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID)
  • Pronounced anti-rheumatic properties
  • Anti-inflammatory
  • Analgesic
  • Antipyretic
  • Uricosuric effect
  • Inhibition of prostaglandin biosynthesis
  • Rapid and complete absorption from the gastro-intestinal tract
  • Metabolized in the liver
  • Undergoes first pass metabolism

Dosage & Administration

  • Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food
  • Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses
  • Elderly patients: Lowest effective dosage recommended
  • Maximum daily dose is 150 mg

Interaction

  • Increased plasma concentrations of lithium and digoxin
  • Increased risk of haemorrhage with the combined use of diclofenac and anticoagulant therapy
  • No influence on antidiabetic agents' clinical effect
  • Nephrotoxicity with cyclosporin and diclofenac concomitant use
  • Serious toxicity when methotrexate and NSAIDs are given within 24 hours of each other
  • Convulsions due to interaction between quinolones and NSAIDs

Contraindications

  • Hypersensitivity to any ingredient of the products
  • Peptic ulcer
  • Hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents
  • Not to be used under occlusive airtight dressings

Side Effects

  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions such as rash and eczema
  • Local irritation and reddening of the skin

Pregnancy & Lactation

  • Employed only for compelling reasons during pregnancy
  • The lowest effective dose should be used
  • Not recommended during the first trimester of pregnancy
  • Insignificant quantity in breast milk

Precautions & Warnings

  • Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
  • Avoid contact with eyes or mucus membranes
  • Wash hands after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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