Diclofen 1% w/w (Gel)

20 gm tube: ৳ 22.14

Medicine Details

Category Details
Generic Diclofenac sodium
Company Opsonin pharma ltd
Also available as
Diclofen 25 mg tablet Diclofen 50 mg tablet Diclofen sr 100 mg tablet Diclofen 75 mg injection Diclofen 125 mg suppository Diclofen 25 mg suppository Diclofen 50 mg suppository Diclofen 100 mg suppository Volifen 1 v spray

Title

  • Diclofenac Sodium Tablets

Categories

  • Medicine
  • Pain Relief
  • Anti-inflammatory
  • Analgesic
  • NSAID

Description

  • A potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, anti-inflammatory, analgesic, and antipyretic properties. Effective for managing various indications including rheumatoid arthritis, osteoarthritis, gout, peri-articular rheumatic disorders, sprains, bruises, dislocations, fractures, soft tissue injuries, primary dysmenorrhoea, post-operative pain, inflammation, and swelling, and more.

Color Options

  • White

Dosage Forms

  • Tablet
  • SR Tablet
  • Dispersible Tablet
  • TR Capsule
  • Suppository
  • Gel
  • Injection

Dosage & Administration

  • Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food.
  • Dose should be reduced in long term use.
  • Children: 1-3 mg of diclofenac/kg body weight daily in divided doses.
  • Elderly patients: In elderly or debilitated patients, the lowest effective dosage is recommended.

Pharmacology

  • Rapid and complete absorption from the gastrointestinal tract.
  • Peak plasma concentrations reached within an average of 2 hours after ingestion.
  • 99.7% bound to plasma proteins.
  • Metabolized in the liver and undergoes first-pass metabolism.

Drug Interactions

  • Lithium and digoxin: may increase plasma concentrations.
  • Anticoagulants: isolated reports of increased risk of hemorrhage.
  • Antidiabetic agents: can be given together without influencing clinical effect.
  • Cyclosporin: cases of nephrotoxicity reported when given concomitantly.
  • Methotrexate: serious toxicity reported when given within 24 hours of NSAIDs.
  • Quinolone antimicrobials: caution should be exercised when considering concomitant therapy.
  • Other NSAIDs and steroids: co-administration may increase frequency of unwanted effects.

Contraindications

  • Hypersensitivity to any ingredient of the product.
  • Peptic ulcer.
  • Hypersensitivity to Diclofenac or other non-steroidal anti-inflammatory agents.
  • Not to be used under occlusive airtight dressings.

Side Effects

  • Mild, rare, and transient adverse effects such as epigastric pain, eructation, nausea, diarrhea, dizziness, headache.
  • Peripheral edema, skin reactions (rash, eczema), local irritation, reddening of the skin, skin rash.

Pregnancy & Lactation

  • Employed only for compelling reasons during pregnancy.
  • Lowest effective dose should be used.
  • Not recommended during the first trimester of pregnancy.
  • Not recommended during lactation due to insignificant quantity detected in breast milk.

Precautions & Warnings

  • Rare instances of peptic ulceration or gastrointestinal bleeding.
  • Close observation for patients with advanced age.
  • Avoid contact with eyes or mucous membranes.
  • Hands should be washed properly after application.
  • Not to be taken by mouth.

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store in a cool and dry place.
  • Protect from light.
  • Store below 30°C.
  • Keep out of the reach of children.

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