Diclonil SR 100 mg (Capsule (Sustained Release))

Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)

Strip Price: ৳ 30.00

Medicine Details

Category	Details
Generic	Diclofenac sodium
Company	Zenith pharmaceuticals ltd
Also available as	Diclonil 50 mg tablet

Indications

Rheumatology
Inflammatory and degenerative forms of rheumatism
Chronic involutive
Polyarthritis
Ankylosing spondylarthritis
Osteoarthritis
Spondylarthroses
Acute gout
Peri-articular rheumatic disorders
Sprain
Bruises
Dislocations
Fractures
Soft tissue injuries
Surgical interventions
Obstetrics and Gynecology
Primary dysmenorrhoea
Episiotomy
Adnexitis
Endometritis
Parametritis
Salpingitis
Mastitis
Otorhinolaryngology
Dentistry
Post-operative and post-traumatic pain
Prevention of pain and treatment of inflammation and swelling

Pharmacology

Potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties. It has some uricosuric effect. Inhibits prostaglandin biosynthesis which causes inflammation, pain, and fever. Rapidly and completely absorbed from the gastro-intestinal tract when taken with or after meal. Metabolized in the liver and undergoes first pass metabolism.

Dosage & Administration

Diclofenac FC Tablet: Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food. Dose should be reduced in long term use.
Diclofenac SR Tablet: Adults: 1 tablet daily, taken whole with liquid, preferably at meal times. Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses. Elderly patients: Lowest effective dosage is recommended.
Diclofenac Dispersible Tablet: Adults: 2-3 tablets daily, maximum daily dose is 150 mg. Children: Not recommended in children except juvenile rheumatoid arthritis.
Diclofenac TR Capsule: One capsule daily, preferably after mealtimes.
Diclofenac Suppository: Adults: 50 mg suppository 2-3 times daily, maximum daily dose is 150 mg.
Diclofenac injection: Adults: 1 ampoule daily, increased to 2 ampoules in serious cases. Diclofenac Gel: 2-4 g of gel applied to the skin 3-4 times daily.

Interaction

Lithium and digoxin
Anticoagulants
Antidiabetic agents
Cyclosporin
Methotrexate
Quinolone antimicrobials
Other NSAIDs and steroids

Contraindications

Patients hypersensitive to any ingredient of the product
Peptic ulcer
Hypersensitivity to Diclofenac
Asthmatic patients with precipitated attacks from acetylsalicylic acid or other prostaglandin synthetase inhibitor drugs
Not to be used under occlusive airtight dressings

Side Effects

Mild, rare and transient adverse effects
Epigastric pain
Eructation
Nausea
Diarrhea
Dizziness
Headache
Peripheral edema
Skin reactions

Pregnancy & Lactation

Should be employed only for compelling reasons during pregnancy. Lowest effective dose should be used. Not recommended during the first trimester of pregnancy. Not recommended during lactation.

Precautions & Warnings

Close observation in patients with peptic ulceration or gastrointestinal bleeding
Avoid contact with eyes or mucus membranes
Hands should be washed properly after applying the gel
Not to be taken by mouth

Therapeutic Class

Drugs for Osteoarthritis
Drugs used for Rheumatoid Arthritis
Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store in a cool and dry place, protected from light. Store below 30°C. Keep out of the reach of children.