Diclorex 25 mg (Tablet)

Unit Price: ৳ 0.54 (100's pack: ৳ 54.00)

Medicine Details

Category Details
Generic Diclofenac sodium
Company Medimet pharmaceuticals ltd
Also available as
Diclorex 50 mg tablet Diclorex rtd 100 mg tablet Diclorex 75 mg injection

Indications

  • Rheumatology
  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Surgery and Traumatology
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Softtissue injuries
  • Surgical interventions
  • Obstetrics and Gynecology
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Otorhinolaryngology
  • Pre-operative medication for the prevention of pain, inflammation, and swelling
  • Dentistry
  • Post-operative and post-traumatic pain, inflammation, and swelling
  • Other indications: For the prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract, renal and biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID)
  • Pronounced anti-rheumatic
  • Anti-inflammatory
  • Analgesic
  • Antipyretic properties
  • Uricosuric effect
  • Inhibiting prostaglandin biosynthesis
  • Rapidly and completely absorbed from the gastro-intestinal tract
  • Peak plasma concentrations reached within an average of 2 hours
  • Metabolized in the liver
  • Undergoes first pass metabolism

Dosage & Administration

  • Diclofenac FC Tablet Adults: 75-150 mg daily in 2 to 3 divided doses
  • Dose should be reduced in long term use
  • Diclofenac SR Tablet: Adult: 1 tablet daily, taken whole with liquid, preferably at meal times
  • Diclofenac Dispersible Tablet: Adults: The recommended daily dosage is 2-3 tablets and the maximum daily dose is 150 mg
  • Diclofenac TR Capsule: One capsule daily
  • Diclofenac Suppository: For adults: 50 mg suppository 2-3 times daily
  • Diclofenac injection: For adults the usual dose is 1 ampoule daily
  • Diclofenac Gel: For external use only. Depending on the size of area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily

Interaction

  • Lithium and digoxin
  • Anticoagulants
  • Antidiabetic agents
  • Cyclosporin
  • Methotrexate
  • Quinolone antimicrobials
  • Other NSAIDs and steroids

Contraindications

  • Patients hypersensitive to any ingredient of the products
  • Peptic ulcer
  • Hypersensitivity to Diclofenac
  • Contra-indicated in asthmatic patient
  • Not to be used under occlusive airtight dressings

Side Effects

  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions
  • Rash
  • Eczema
  • Local irritation
  • Reddening of the skin
  • Skin rash

Pregnancy & Lactation

  • Employed only for compelling reasons
  • Lowest effective dose should be used
  • Not recommended during the first trimester
  • Not recommended during pregnancy
  • Insignificant quantity of Diclofenac may be detected in breast milk

Precautions & Warnings

  • Peptic ulceration or gastrointestinal bleeding
  • Close observation for patients with advanced age
  • Not to come in contact with the eyes or mucus membranes
  • Not to be taken by mouth

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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