Diclovir 50 mg (Tablet)
Unit Price: ৳ 0.75 (100's pack: ৳ 75.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Virgo pharmaceuticals ltd |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for the prevention of pain, inflammation, and swelling
- Post-operative and post-traumatic pain
- Pain and treatment of inflammation and swelling for patients operated in the urogenital tract, renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- Metabolized in the liver
- First pass metabolism
Dosage & Administration
- Adults: 75-150 mg daily in 2 to 3 divided doses
- Preferably after food
- Reduction of dose in long term use
- Diclofenac SR Tablet: 1 tablet daily for adults
- Children: 1-3 mg of diclofenac/kg body weight daily
- Elderly patients: Lowest effective dosage is recommended
- Diclofenac Dispersible Tablet: Recommended daily dosage is 2-3 tablets
- Maximum daily dose for adults: 150 mg
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository: 50 mg suppository 2-3 times daily
- Maximum daily dose: 150 mg
- Diclofenac injection: Usual dose is 1 ampoule daily
- Diclofenac Gel: Applied to the skin 3-4 times daily for external use
Interaction
- May increase plasma concentrations of lithium and digoxin
- Isolated reports of an increased risk of hemorrhage with combined use of diclofenac and anticoagulant therapy
- Can be given together with oral antidiabetic agents without influencing their clinical effect
- Cases of nephrotoxicity reported in patients receiving cyclosporin and diclofenac concomitantly
- Serious toxicity reported when methotrexate and NSAIDs are given within 24 hours of each other
- Convulsions may occur due to an interaction between quinolones and NSAIDs
- Co-administration of diclofenac with other systemic NSAIDs and steroids may increase unwanted effects
- Plasma levels of each is lowered with aspirin, although no clinical significance is known
Contraindications
- Hypersensitivity to any ingredient of the product
- Peptic ulcer
- Hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents
- Contra-indicated in asthmatic patients in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation
- Reddening of the skin
- Skin rash
Pregnancy & Lactation
- Employed only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during the first trimester of pregnancy
- Not recommended during pregnancy due to insufficient clinical data
- Insignificant quantity detected in breast milk with no undesirable effects on the infant
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Close observation for patients with advanced age
- Avoid contact with the eyes or mucus membranes for Diclofenac Gel
- Hands should be washed properly after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children