Dix Plus (75 mg+20 mg)/2 ml (IM Injection)

2 ml ampoule: ৳ 9.50 (2 x 5: ৳ 95.00)

Medicine Details

Indications

  • Relief of pain and inflammation
  • Arthritic conditions
  • Musculoskeletal disorders
  • Painful conditions resulting from trauma
  • Renal colic
  • Local anaesthetic
  • Minimization of pain at injection site

Pharmacology

  • Potent nonsteroidal anti-inflammatory drug (NSAID)
  • Marked analgesic and antipyretic properties
  • Uricosuric effects
  • Inhibition of prostaglandin synthesis
  • Effects of Diclofenac
  • Effects of Lidocaine
  • Onset and duration of anesthesia for Lidocaine

Dosage & Administration

  • Adult dosage
  • Severe cases dosage
  • Renal colic dosage
  • Children dosage
  • Elderly patients dosage

Interaction

  • Interaction with Lithium and Digoxin
  • Interaction with Anticoagulants
  • Interaction with Antidiabetic agents
  • Interaction with Cyclosporin
  • Interaction with Methotrexate
  • Interaction with Quinolone antimicrobials
  • Interaction with Other NSAIDs and steroids
  • Interaction with Diuretics

Contraindications

  • Hypersensitivity to Diclofenac
  • Peptic ulcer or gastrointestinal bleeding
  • Hypersensitivity to local anaesthetics
  • Adams-Stokes syndrome
  • Severe degrees of heart block
  • Hypersensitivity to excipients

Side Effects

  • Mild and transient side effects
  • Gastrointestinal discomfort
  • Nausea and diarrhea
  • Bleeding
  • Injection site disorders
  • Abscesses and local necrosis
  • Adverse effects due to Lidocaine
  • CNS related adverse effects

Pregnancy & Lactation

  • Use during pregnancy
  • Lowest effective dosage
  • Not recommended during last trimester
  • Detection in breast milk
  • No undesirable effects on the infant

Precautions & Warnings

  • Renal insufficiency precautions
  • Hepatic precautions
  • Deterioration of renal function
  • Monitoring renal function
  • Monitoring liver function tests

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Storage temperature not exceeding 30°C
  • Dry place
  • Protected from light

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