Tenoren 50 mg (Tablet)
Unit Price: ৳ 0.77 (10 x 20: ৳ 154.00)
Strip Price: ৳ 15.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Atenolol |
| Company | Aci limited |
| Also available as |
Title and Categories
- Tenoren
- Hypertension Medication
- Angina Pectoris Medication
- Myocardial Infarction Medication
- Beta-blocker
Dimensions
- N/A
Color Options
- N/A
Functions
- Management of hypertension
- Long-term management of angina pectoris
- Management of hemodynamically stable patients with definite or suspected acute myocardial infarction
Materials
- N/A
Technical Specifications
- Pharmacological classification as a β1 selective (cardioselective) β-adrenergic receptor antagonist
- Hydrophilic nature affecting cell membrane penetration
Design Elements
- N/A
Usability Features
- Once-daily dosing for 24-hour control
- Initial dose of 50 mg, with option to increase to 100mg for hypertension
- Initial dose of 50 mg, with option to increase to 200 mg for angina pectoris
- Appropriate administration during acute myocardial infarction
Interactions
- Additive effects with catecholamine-depleting drugs
- Additive effects with calcium channel blockers
- Potential adverse effects when used with disopyramide or amiodarone
- Exacerbation of rebound hypertension when coadministered with clonidine
- Decrease in hypotensive effects when used with prostaglandin synthase inhibiting drugs
- Increased risk of severe allergic reactions
- Potential increase in risk of bradycardia when used concomitantly with digitalis glycosides
Contraindications
- Sinus bradycardia
- Heart block greater than first degree
- Cardiogenic shock
- Overt cardiac failure
- Hypersensitivity to atenolol or any of the drug product’s components
Side Effects
- Bradycardia
- Hypotension
- Agranulocytosis
- Allergic reactions (fever, sore throat, respiratory distress)
- Reversible mental depression
- Ischemic gastrointestinal disorders
- Skin rashes
- Dry eyes
Pregnancy & Lactation
- Pregnancy Category D
- Caution in nursing women due to risk of bradycardia in breast-fed infants
Precautions & Warnings
- Evaluation of patients already on beta blockers before administration
- Aggravation of peripheral arterial circulatory disorders
- Caution in patients with impaired renal function
- Cautious dose selection for elderly patients and those with renal impairment
- Assessment of renal function for patients with hypertension or myocardial infarction
- Adjustment of dosage for patients with severe impairment of renal function
- Lower starting dose for renal impaired or elderly patients with hypertension
- Special monitoring for patients on hemodialysis
Use in Special Populations
- Dosage adjustment for elderly patients or those with renal impairment
- Maximum recommended oral dosages based on creatinine clearance
Overdose Effects
- Reported overdoses surviving acute doses as high as 5g
- Lethargy
- Respiratory disorders
- Bradycardia
- Congestive heart failure
- Hypotension
- Bronchospasm
- Hypoglycemia
- Treatment may require induced emesis, gastric lavage, activated charcoal administration, and hemodialysis
- Potential need for intensive support care and facilities for cardiac and respiratory support
Therapeutic Class
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Expiry date adherence
- Keep out of reach of children
- Dispensing only on prescription
Others
- May be used alone or concomitantly with other antihypertensive agents
- Pharmacological synthesis aimed at selective β1 (cardiac) receptor antagonism
- May be used concomitantly with diuretic therapy for hypertension management
- 24-hour control with once-daily dosing
- Option for incremental dosage increase based on patient response