Edifenac 50 mg (Tablet)

Unit Price: ৳ 0.83 (100's pack: ৳ 83.00)

Medicine Details

Indications

  • Inflammatory rheumatism
  • Degenerative rheumatism
  • Chronic involutive rheumatism
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication
  • Post-operative pain
  • Post-traumatic pain
  • Urogenital tract pain
  • Renal colic
  • Biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug
  • Anti-rheumatic
  • Analgesic
  • Antipyretic
  • Uricosuric effect
  • Inhibition of prostaglandin biosynthesis
  • Rapid and complete absorption from gastro-intestinal tract
  • Peak plasma concentrations reached within 2 hours
  • Metabolized in the liver
  • Undergoes first-pass metabolism

Dosage and Administration

  • Adult dosage: 75-150 mg daily
  • Dosage reduction for long term use
  • Different dosage for different tablet types
  • Supplementation with conventional tablets
  • Specific dosage for children
  • Recommended daily dosage for adults and children
  • Maximum daily dose
  • Usage for external application

Interaction

  • Increased plasma concentrations of lithium and digoxin
  • Isolated reports of increased risk of haemorrhage with anticoagulant therapy
  • Can be given together with oral antidiabetic agents
  • Cases of nephrotoxicity with cyclosporin
  • Cases of serious toxicity with methotrexate
  • Convulsions with quinolone antimicrobials
  • Increased frequency of unwanted effects with other NSAIDs and steroids

Contraindications

  • Hypersensitivity to any ingredient
  • Peptic ulcer
  • Hypersensitivity to Diclofenac or other NSAIDs
  • Contra-indicated in asthmatic patients
  • Not for use under occlusive airtight dressings

Side Effects

  • Mild, rare, and transient adverse effects
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions
  • Local irritation
  • Reddening of the skin
  • Skin rash

Pregnancy and Lactation

  • Use only for compelling reasons during pregnancy
  • Lowest effective dose in pregnancy
  • Not recommended during first trimester
  • Not recommended during lactation

Precautions and Warnings

  • Close observation for peptic ulceration or gastrointestinal bleeding
  • Caution regarding eye and mucous membrane contact
  • Proper hand washing after application
  • Not to be taken by mouth

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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