Edifenac 50 mg (Tablet)
Unit Price: ৳ 0.83 (100's pack: ৳ 83.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Edruc limited |
| Also available as |
Indications
- Inflammatory rheumatism
- Degenerative rheumatism
- Chronic involutive rheumatism
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication
- Post-operative pain
- Post-traumatic pain
- Urogenital tract pain
- Renal colic
- Biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from gastro-intestinal tract
- Peak plasma concentrations reached within 2 hours
- Metabolized in the liver
- Undergoes first-pass metabolism
Dosage and Administration
- Adult dosage: 75-150 mg daily
- Dosage reduction for long term use
- Different dosage for different tablet types
- Supplementation with conventional tablets
- Specific dosage for children
- Recommended daily dosage for adults and children
- Maximum daily dose
- Usage for external application
Interaction
- Increased plasma concentrations of lithium and digoxin
- Isolated reports of increased risk of haemorrhage with anticoagulant therapy
- Can be given together with oral antidiabetic agents
- Cases of nephrotoxicity with cyclosporin
- Cases of serious toxicity with methotrexate
- Convulsions with quinolone antimicrobials
- Increased frequency of unwanted effects with other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other NSAIDs
- Contra-indicated in asthmatic patients
- Not for use under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions
- Local irritation
- Reddening of the skin
- Skin rash
Pregnancy and Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose in pregnancy
- Not recommended during first trimester
- Not recommended during lactation
Precautions and Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Caution regarding eye and mucous membrane contact
- Proper hand washing after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children