E-Fenac 50 mg (Tablet)
Unit Price: ৳ 0.50 (100's pack: ৳ 50.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Reliance pharmaceuticals ltd |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for the prevention of pain, inflammation, and swelling in Otorhinolaryngology
- Post-operative and post-traumatic pain, inflammation, and swelling in dentistry
- Prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract, renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Pronounced anti-rheumatic properties
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
- Metabolized in the liver
- Undergoes first-pass metabolism
Dosage & Administration
- Adult dosage: 75-150 mg daily in 2 to 3 divided doses
- Dose should be reduced in long term use
- Children dosage: 1-3 mg of diclofenac/kg body weight daily in divided doses
- Elderly patients: Lowest effective dosage is recommended
- Recommended daily dosage for Diclofenac Dispersible Tablet: 2-3 tablets
Interaction
- May increase plasma concentrations of lithium and digoxin
- Increased risk of hemorrhage with combined use of diclofenac and anticoagulant therapy
- Can be given together with oral antidiabetic agents without influencing their clinical effect
- Cases of nephrotoxicity reported in patients receiving cyclosporin and diclofenac concomitantly
- Serious toxicity reported when methotrexate and NSAIDs are given within 24 hours of each other
- Convulsions may occur due to interaction between quinolones and NSAIDs
- Co-administration with other systemic NSAIDs and steroids may increase frequency of unwanted effects
Contraindications
- Hypersensitive to any ingredient of the product
- Peptic ulcer
- Hypersensitivity to Diclofenac like other non-steroidal anti-inflammatory agents
- Contra-indicated in asthmatic patients
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Should be employed only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
- Insignificant quantity may be detected in breast milk
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Advanced age patients should be kept under close observation
- Avoid contact with eyes or mucous membranes
- Hands should be washed properly after application
Therapeutic Class
Drugs for Osteoarthritis, Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Store in a cool and dry place, protected from light, Keep out of the reach of children