Erdon 1% w/w (Gel)

50 gm tube: ৳ 100.00

Medicine Details

Indications

  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for the prevention of pain, inflammation, and swelling
  • Post-operative and post-traumatic pain
  • Pain and treatment of inflammation and swelling of patients operated in the urogenital tract
  • Renal and biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID)
  • Pronounced anti-rheumatic, anti-inflammatory, analgesic, and antipyretic properties
  • Uricosuric effect
  • Inhibits prostaglandin biosynthesis
  • Rapid and complete absorption from the gastro-intestinal tract
  • Metabolized in the liver

Dosage & Administration

  • Adults: 75-150 mg daily in 2 to 3 divided doses
  • Adults: 1 tablet daily (SR Tablet)
  • Children: 1-3 mg of diclofenac/kg body weight daily
  • One capsule daily (TR Capsule)
  • For adults: 50 mg suppository 2-3 times daily
  • For adults: 1 ampoule daily (injection)
  • External use: 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily

Interaction

  • May increase plasma concentrations of lithium and digoxin
  • Increased risk of haemorrhage with combined use of diclofenac and anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Cases of nephrotoxicity reported in patients receiving cyclosporin and diclofenac concomitantly
  • Serious toxicity reported when methotrexate and NSAIDs are given within 24 hours of each other
  • Convulsions may occur due to an interaction between quinolones and NSAIDs

Contraindications

  • Hypersensitive to any ingredient of the products
  • Peptic ulcer
  • Hypersensitivity to Diclofenac
  • Contra-indicated in asthmatic patient

Side Effects

  • Mild, rare and transient adverse effects
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions such as rash and eczema
  • Local irritation and reddening of the skin

Pregnancy & Lactation

  • Employed only for compelling reasons during pregnancy
  • Lowest effective dose should be used
  • Not recommended during the first trimester of pregnancy

Precautions & Warnings

  • Close observation in patients with advanced age
  • Gel should not be allowed to come in contact with the eyes or mucus membranes
  • Hands should be washed properly after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Store below 30°C

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