Genac 50 mg (Tablet)
Unit Price: ৳ 1.20 (10 x 10: ৳ 120.00)
Strip Price: ৳ 12.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Sprain
- Primary dysmenorrhoea
- Pre-operative medication for the prevention of pain
- Post-operative and post-traumatic pain
- Treatment of inflammation and swelling of patients operated in the urogenital tract
- Renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- 99.7% bound to plasma proteins
- Metabolized in the liver
Dosage & Administration
- Adults: 75-150 mg daily in 2 to 3 divided doses
- Preferably after food
- Diclofenac SR Tablet: 1 tablet daily for adults
- Elderly patients: lowest effective dosage is recommended
- Diclofenac Dispersible Tablet: 2-3 tablets daily for adults
- Maximum daily dose is 150 mg
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository: 50 mg suppository 2-3 times daily
- Maximum daily dose is 150 mg
- Diclofenac Gel: 2-4 g applied to the skin 3-4 times daily
- For external use only
Interaction
- May increase plasma concentrations of lithium and digoxin
- Reports of an increased risk of haemorrhage with the combined use of diclofenac and anticoagulant therapy
- Can be given together with oral antidiabetic agents without influencing their clinical effect
- Cases of nephrotoxicity reported in patients receiving cyclosporin and diclofenac concomitantly
- Serious toxicity reported when methotrexate and NSAIDs are given within 24 hours of each other
- Convulsions may occur due to an interaction between quinolones and NSAIDs
- Co-administration of diclofenac with other systemic NSAIDs and steroids may increase the frequency of unwanted effects
Contraindications
- Hypersensitivity to any ingredient of the products
- Peptic ulcer
- Hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents
- Contra-indicated in asthmatic patient in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin and skin rash
Pregnancy & Lactation
- Should be employed only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Diclofenac Sodium Gel is not recommended during pregnancy
- Very insignificant quantity may be detected in breast milk but no undesirable effects on the infant to be expected
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Elderly patients should be kept under close observation
- Not to come in contact with the eyes or mucus membranes
- Hands should be washed properly after application
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children