Hi-Fenac TR 100 mg (Capsule (Timed Release))
Unit Price: ৳ 3.00 (100's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Hudson pharmaceuticals ltd |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for prevention of pain, inflammation, and swelling
- Post-operative and post-traumatic pain, inflammation, and swelling
- Prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract, renal and biliary colic
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
- Metabolized in the liver
- First pass metabolism
Dosage & Administration
- Adult dosage: 75-150 mg daily in 2 to 3 divided doses, preferably after food
- Children dosage: 1-3 mg of diclofenac/kg body weight daily in divided doses
- Elderly patients dosage: Lowest effective dosage recommended
- Maximum dosage: 150 mg daily
- Suppository dosage: 50 mg 2-3 times daily
- Gel application: 2-4 g applied to the skin 3-4 times daily
- Capsule dosage: One capsule daily
Interaction
- Increased plasma concentrations of lithium and digoxin
- Possible increased risk of hemorrhage with anticoagulant therapy
- No influence on clinical effect of oral antidiabetic agents
- Reported cases of nephrotoxicity with cyclosporin
- Potential serious toxicity when co-administered with methotrexate
- Possible convulsions with quinolone antimicrobials
- Increased frequency of unwanted effects when co-administered with other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroidal anti-inflammatory agents
- Contraindicated in asthmatic patients with precipitated attacks by acetylsalicylic acid or other prostaglandin synthetase inhibitors
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions like rash and eczema
- Local skin irritation and reddening
- Skin rash
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose to be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation due to detection in breast milk
- No undesirable effects on the infant expected
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Age-related observation
- Avoid contact with eyes or mucus membranes
- Hand washing after application
- Avoid oral ingestion
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children