Intafenac Plus (75 mg+20 mg)/2 ml (IM Injection)
2 ml ampoule: ৳ 15.00 (2 x 5: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium lidocaine hydrochloride |
| Company | Incepta pharmaceuticals ltd |
Indications
- relief of pain and inflammation
- rheumatoid arthritis
- osteoarthritis
- juvenile chronic arthritis
- ankylosing spondylitis
- acute gout
- periarthritis
- tendinitis
- tenosynovitis
- bursitis
- trauma pain relief
- fracture pain relief
- low back pain relief
- musculoskeletal pain relief
- pain relief after surgery
- pain relief for renal colic
- local anaesthetic action
- minimized pain at injection site
Pharmacology
- nonsteroidal antiinflammatory drug (NSAID)
- analgesic
- antipyretic
- uricosuric effects
- inhibition of prostaglandin synthesis
- inhibition of cyclooxygenase
- rapid peak plasma concentration
- local anaesthetic drug
- impairment of nerve impulse generation and conduction
Dosage & Administration
- adult dosage by intramuscular injection
- renal colic dosage
- children's dosage for juvenile chronic arthritis
- recommended elderly patient dosage
Interaction
- interaction with lithium and digoxin
- interaction with anticoagulants
- interaction with antidiabetic agents
- interaction with cyclosporin
- interaction with methotrexate
- interaction with quinolone antimicrobials
- interaction with other NSAIDs and steroids
- interaction with diuretics
Contraindications
- hypersensitivity to diclofenac
- active or suspected peptic ulcer
- gastrointestinal bleeding
- asthma, urticaria, or acute rhinitis induced by NSAIDs
- hypersensitivity to lidocaine
- Adams-Stokes syndrome
- severe heart block
- hypersensitivity to excipients
Side Effects
- mild and transient side effects
- gastrointestinal discomfort
- nausea
- diarrhea
- bleeding
- injection site disorder
- abscesses
- local necrosis
- CNS-related adverse effects
Pregnancy & Lactation
- avoidance during pregnancy
- use lowest effective dosage if necessary
- avoidance during last trimester
- small quantities in breast milk
Precautions & Warnings
- close observation for severe hepatic, cardiac, or renal insufficiency
- monitoring for deteriorating renal function
- monitoring for abnormal liver function tests
- monitoring for long term NSAID use
Therapeutic Class
- drugs for osteoarthritis
- drugs for rheumatoid arthritis
- non-steroidal anti-inflammatory drugs (NSAIDs)
Storage Conditions
- storage temperature not exceeding 30°C
- dry place storage
- protected from light
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