Megafen 50 mg (Tablet)
Unit Price: ৳ 0.81 (10 x 10: ৳ 81.00)
Strip Price: ৳ 8.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatology
- Inflammatory conditions
- Degenerative rheumatism
- Chronic polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Sprains
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Obstetrics
- Gynecology
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Otorhinolaryngology
- Pre-operative medication
- Post-operative pain relief
- Post-traumatic pain relief
- Urogenital tract pain relief
- Renal colic pain relief
- Biliary colic pain relief
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Prostaglandin biosynthesis inhibition
- Rapid absorption from gastrointestinal tract
- High plasma protein binding
- Liver metabolism
Dosage & Administration
- Adult dosage range: 75-150 mg daily
- Divided dosing
- Reduction of long-term use dosage
- Specific dosage for different tablet types (FC, SR, Dispersible, TR)
- Elderly patient dosage considerations
- Suppository dosage and administration
- Gel application frequency and technique
Interaction
- Increase in plasma concentrations of lithium and digoxin
- Risk of haemorrhage with anticoagulants
- Clinical effect compatibility with antidiabetic agents
- Nephrotoxicity risk with cyclosporin
- Serious toxicity risk with methotrexate
- Convulsion risk with quinolone antimicrobials
- Unwanted effects frequency increase with NSAIDs and steroids
- Lowered plasma levels when co-administered with aspirin
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other NSAIDs
- Asthmatic patients with specific reactions to aspirin or prostaglandin synthetase inhibitor
- Avoid use under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions (rash, eczema)
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Insignificant quantity in breast milk
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Close observation for advanced age patients
- Avoid contact with eyes or mucus membranes
- Proper hand washing after application
- Avoid ingestion
Therapeutic Class
- Osteoarthritis drugs
- Rheumatoid Arthritis drugs
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Cool and dry storage
- Protected from light
- Temperature below 30°C
- Keep out of reach of children