Megafen 75 mg/3 ml (IM Injection)
3 ml ampoule: ৳ 10.18 (5 x 4: ৳ 203.60)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Surgery and Traumatology
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Obstetrics and Gynecology
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Otorhinolaryngology
- Pre-operative medication for the prevention of pain
- Inflammation
- Swelling
- Dentistry
- Post-operative and post-traumatic pain
- Inflammation
- Swelling
- Other indications
- Prevention of pain and treatment of inflammation
- Swelling of patients operated in the urogenital tract
- Renal and biliary colic
Pharmacology
- Non-steroidal anti-inflammatory drug
- Potent anti-rheumatic properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
- Peak plasma concentrations reached within an average of 2 hours
- 99.7% bound to plasma proteins
- Metabolized in the liver
Dosage & Administration
- Diclofenac FC Tablet for adults: 75-150 mg daily in 2 to 3 divided doses
- Dose should be reduced in long term use
- Diclofenac SR Tablet for adults: 1 tablet daily, taken whole with liquid, preferably at meal times
- Diclofenac Dispersible Tablet for adults: 2-3 tablets recommended daily dosage
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository for adults: 50 mg suppository 2-3 times daily
- Diclofenac injection for adults: 1 ampoule daily
- Diclofenac Gel: For external use, 2-4 g applied to the skin 3-4 times daily
Interaction
- Potential drug interactions with Lithium and digoxin
- Potential drug interactions with Anticoagulants
- Potential drug interactions with Antidiabetic agents
- Potential drug interactions with Cyclosporin
- Potential drug interactions with Methotrexate
- Potential drug interactions with Quinolone antimicrobials
- Potential drug interactions with Other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient of the products
- Peptic ulcer
- Hypersensitivity to Diclofenac
- Contra-indicated in asthmatic patients
Side Effects
- Mild, rare and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Insignificant quantity detected in breast milk
- No undesirable effects on the infant expected
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Avoid contact with eyes or mucus membranes
- Hands should be washed properly after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children