Mobifen 50 mg (Tablet)

Unit Price: ৳ 0.88 (10 x 10: ৳ 88.00)
Strip Price: ৳ 8.80

Medicine Details

Category Details
Generic Diclofenac sodium
Company Aci limited
Also available as
Mobifen 125 mg suppository Mobifen 25 mg suppository Mobifen 50 mg suppository Mobifen sr 100 mg capsule

Indications

  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Acute gout
  • Sprain
  • Bruises
  • Dislocations
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for pain, inflammation, and swelling
  • Post-operative pain, inflammation, and swelling
  • Treatment of pain, inflammation, and swelling post-trauma
  • Pain and treatment of inflammation and swelling in the urogenital tract
  • Renal and biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID)
  • Pronounced anti-rheumatic properties
  • Anti-inflammatory
  • Analgesic
  • Antipyretic
  • Uricosuric effect
  • Inhibits prostaglandin biosynthesis
  • Rapid and complete absorption from the gastro-intestinal tract
  • Peak plasma concentrations reached within average of 2 hours
  • 99.7% bound to plasma proteins
  • Metabolized in the liver

Dosage & Administration

  • Adult dosage: 75-150 mg daily in 2 to 3 divided doses
  • Dosage should be reduced in long-term use
  • Children dosage: 1-3 mg of diclofenac per kg body weight daily in divided doses
  • Recommended daily dosage for adults of diclofenac dispersible tablet is 2-3 tablets
  • Maximum daily dose of diclofenac suppository is 150 mg
  • For external use only: 2-4 g of diclofenac gel to be applied to the skin 3-4 times daily

Interaction

  • May increase plasma concentrations of lithium and digoxin
  • Isolated reports of increased risk of hemorrhage with combined use of diclofenac and anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Caution with concomitant therapy of NSAID and quinolones
  • Co-administration with other systemic NSAIDs and steroids may increase frequency of unwanted effects

Contraindications

  • Hypersensitivity to any ingredient of the products
  • Peptic ulcer
  • Hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents
  • Contra-indicated in asthmatic patients in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
  • Not to be used under occlusive airtight dressings

Side Effects

  • Adverse effects are mild, rare, and transient
  • May cause epigastric pain, eructation, nausea, diarrhea, dizziness, headache, peripheral edema, skin reactions such as rash and eczema
  • May cause local irritation, reddening of the skin, and skin rash

Pregnancy & Lactation

  • Should be employed only for compelling reasons during pregnancy
  • Lowest effective dose should be used
  • Not recommended during the first trimester of pregnancy
  • Not recommended during lactation

Precautions & Warnings

  • Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
  • Close observation for patients with advanced age
  • Gel should not come in contact with eyes or mucous membranes
  • Hands should be washed properly after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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