Mobifen Plus (75 mg+20 mg)/2 ml (IM Injection)

Indications

• Relief of pain and inflammation
• Treatment of arthritic conditions
• Management of acute musculoskeletal disorders
• Pain control after trauma or surgery

Pharmacology

• Potent nonsteroidal antiinflammatory drug (NSAID)
• Marked analgesic and antipyretic properties
• Inhibition of prostaglandin synthesis
• Rapid action of Lidocaine as a local anaesthetic

Dosage & Administration

• Adult dosage by intramuscular injection
• Specific dosage for renal colic
• Children's dosage for juvenile chronic arthritis
• Recommended dosage for elderly patients

Interactions

• Increased plasma concentrations of Lithium and Digoxin
• Possible risk of haemorrhage with anticoagulant therapy
• Compatibility with oral antidiabetic agents
• Potential nephrotoxicity when used with Cyclosporin
• Caution with concomitant use of quinolone antimicrobials and NSAIDs
• Possible increase in unwanted effects when co-administered with other NSAIDs and steroids
• Inhibition of diuretics activity and potential impact on serum potassium levels

Contraindications

• Hypersensitivity to Diclofenac
• Active or suspected peptic ulcer or gastrointestinal bleeding
• Hypersensitivity to local anaesthetics of the amide type
• Adams-Stokes syndrome or severe heart block
• Hypersensitivity to excipients in the formulation

Side Effects

• Mild and transient gastrointestinal discomfort
• Nausea and diarrhea
• Bleeding
• Injection site disorder
• Rare instances of abscesses and local necrosis
• CNS reactions such as drowsiness and dizziness

Pregnancy & Lactation

• Not recommended during pregnancy unless compelling reasons exist
• Use the lowest effective dosage if required during pregnancy
• Avoid use during the last trimester of pregnancy
• Small quantities may be detected in breast milk with no expected undesirable effects on the infant

Precautions & Warnings

• Close observation for patients with severe hepatic, cardiac, or renal insufficiency
• Monitor renal function for patients using NSAIDs
• Discontinue if abnormal liver function tests appear
• Long-term monitoring for patients on NSAIDs
• Close observation for hepatic, cardiac, and renal function

Therapeutic Class

• Drugs for Osteoarthritis
• Drugs used for Rheumatoid Arthritis
• Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

• Store at temperatures not exceeding 30°C
• Keep in a dry place
• Protected from light

Related Brands

• Relnac Plus (75 mg+20 mg)/2 ml (IM Injection) - albion-laboratories-limited
• C-Fenac Plus (75 mg+20 mg)/2 ml (IM Injection) - chemist-laboratories-ltd
• Erdon-Plus (75 mg+20 mg)/2 ml (IM Injection) - aristopharma-ltd
• Panlid (75 mg+20 mg)/2 ml (IM Injection) - pacific-pharmaceuticals-ltd
• Orafen Plus (75 mg+20 mg)/2 ml (IM Injection) - rangs-pharmaceuticals-ltd