Proflam Lido (75 mg+20 mg)/2 ml (IM Injection)

2 ml ampoule: ৳ 15.05 (5's pack: ৳ 75.24)

Medicine Details

Category Details
Generic Diclofenac sodium lidocaine hydrochloride
Company Novo healthcare and pharma ltd

Title

  • Diclofenac Sodium and Lidocaine Injection

Categories

  • Pain Relief
  • Anti-inflammatory
  • Anesthetic
  • Musculoskeletal Disorders
  • Arthritic Conditions
  • NSAID

Description

  • The injection used to relief all grades of pain and inflammation in a wide range of conditions
  • Contains Diclofenac Sodium and Lidocaine
  • Peak plasma concentration achieved within half an hour following injection
  • Used for orthopedic, dental, and other minor surgeries
  • Acts as a local anaesthetic to minimize pain at the injection site
  • Mild and transient side effects, can be discontinued if serious side effects occur

Dimensions

  • Standard ampoule size

Color options

  • Clear solution

Functions

  • Relieves pain and inflammation
  • Acts as a local anaesthetic

Materials

  • Diclofenac Sodium
  • Lidocaine
  • Sodium Metabisulphite
  • Disodium Edetate
  • Benzyl Alcohol
  • Sodium Hydroxide
  • Propylene Glycol

Technical specifications

  • Potent nonsteroidal anti-inflammatory drug (NSAID)
  • Marked analgesic and antipyretic properties
  • Has some uricosuric effects
  • Inhibits prostaglandin synthesis
  • Impairs the generation and conduction of nerve impulses
  • More rapid onset and 1-2 hours duration of anaesthesia for Lidocaine Hydrochloride

Design elements

  • Standard ampoule design

Usability features

  • Intramuscular administration
  • Single or twice daily dosage for adults
  • Dosage adjusted based on body weight for children
  • Lowest effective dosage recommended for elderly patients
  • Close observation for patients with severe hepatic, cardiac, or renal insufficiency

Interaction

  • May increase plasma concentrations of Lithium and Digoxin
  • Reports of increased risk of hemorrhage with anticoagulant therapy
  • Can be given together with oral antidiabetic agents without influencing their clinical effect
  • Cases of nephrotoxicity reported when used concomitantly with Cyclosporin
  • Caution needed when considering concomitant therapy of NSAIDs and quinolones
  • Potential increase in unwanted effects when co-administered with other NSAIDs and steroids
  • Inhibition of diuretic activity leading to increased serum potassium levels

Contraindications

  • Hypersensitivity to Diclofenac or local anaesthetics of the amide type
  • Active or suspected peptic ulcer or gastrointestinal bleeding
  • Attacks of asthma, urticaria, or acute rhinitis precipitated by Aspirin or other NSAIDs
  • Adams-Stokes syndrome or severe AV or intraventricular heart block in the absence of an artificial pacemaker
  • Hypersensitivity to any of the excipients used in the formulation

Side effects

  • Gastrointestinal discomfort
  • Nausea
  • Diarrhea
  • Bleeding
  • Injection site disorder
  • Rare instances of abscesses and local necrosis
  • CNS reactions such as drowsiness, dizziness, confusion
  • Dose-related adverse effects due to Lidocaine mainly involving the CNS

Pregnancy

  • Not recommended during pregnancy unless compelling reasons exist
  • Lowest effective dosage should be used
  • Not recommended during the last trimester of pregnancy
  • Very small quantities may be detected in breast milk with no undesirable effects on the infant

Precautions

  • Close observation for patients with severe hepatic, cardiac, or renal insufficiency
  • Lowest effective dose and renal function monitoring recommended
  • Discontinue if abnormal liver function tests persist or worsen
  • Long term monitoring of renal, hepatic function, and blood counts for all patients receiving NSAIDs

Therapeutic class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage conditions

  • Store at temperature not exceeding 30°C
  • Store in a dry place
  • Protected from light

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